Scopus
🔓 Açık Erişim
Viscum album L. homogenizer-assisted and ultrasound-assisted extracts as potential sources of bioactive compounds
Journal of Food Biochemistry · Eylül 2020
Makale Bilgileri
DergiJournal of Food Biochemistry
Yayın TarihiEylül 2020
Cilt / Sayfa44
Scopus ID2-s2.0-85088477583
Erişim🔓 Açık Erişim
Özet
Viscum album L. (Mistletoe) is one of the most famous plants in many countries utilized for several purposes. The current study aimed to describe chemical profiles and biological activities of homogenizer-assisted extract (HAE) and ultrasound-assisted extract (UAE)) of V. album parts (leaf, fruits, and seeds). Antioxidant (radical scavenging, reducing power, metal chelation, and phosphomolybdenum assays) and enzyme inhibitory properties (cholinesterases, amylase, glucosidase, and tyrosinase) were selected for biological evaluation. Chemical profiles were studied by HPLC-MS/MS and 32 compounds were identified in the extracts; caffeoylquinic acids and its derivatives, dimethylated flavonoids were the most significant compounds. Generally, the leaf extracts exhibited the best antioxidant and enzyme inhibitory effects in our tests. Multivariate analysis was performed to obtain more information for these data, then strong correlations between total bioactive compounds and tested parameters were observed. The present findings encourage us to further investigate V. album as a potential candidate for pharmaceutical and nutraceutical applications. Practical applications: Viscum album L. commonly called European mistletoe is a woody perennial shrub growing on coniferous trees with lathery leaves, small flowers, and white berries. It belongs to the Santalaceae R. Br. family from Europe and western/southern Asia. Traditional medicine recognizes mistletoe as a folk remedy to manage inflammation, hypertension, ulcers, and other diseases due to the presence of different bioactive compounds, among them mistletoe lectins and viscotoxins. Recent studies documented the possible therapeutic applications of Viscum extracts in association with cancer's therapy leading to improvements in health and patient's quality of life. Thus, this work gives novel data regarding the phytochemical characterizations and antioxidant/enzymatic inhibitor activities of different types of extracts from seeds, leaves, and fruits of Viscum L. obtained by homogenizer-assisted and ultrasound-assisted techniques, in order to increase the data set of potential applications in medicine.
Yazarlar (9)
1
Azzurra Stefanucci
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
E. J. Llorent-Martínez
4
Marilisa Pia Dimmito
5
Alice Della Valle
6
Stefano Pieretti
7
Gunes Ak
8
Kouadio Ibrahime Sinan
9
Adriano Mollica
Anahtar Kelimeler
antioxidant
caffeoylquinic acids
glucosidase
multivariate
phyto-pharmaceutics
Viscum
Kurumlar
Istituto Superiore Di Sanita
Rome Italy
Selçuk Üniversitesi
Selçuklu Turkey
Universidad de Jaén
Jaen Spain
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
Metrikler
35
Atıf
9
Yazar
6
Anahtar Kelime