Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
A comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniques
Applied Sciences (Switzerland) · Eylül 2020
YÖKSİS Kayıtları
A comparative bio-evaluation and chemical profiles of calendula officinalis L. extracts prepared via different extraction techniques
APPLIED SCIENCES-BASEL · 2020 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiApplied Sciences (Switzerland)
Yayın TarihiEylül 2020
Cilt / Sayfa10
Scopus ID2-s2.0-85090223160
Erişim🔓 Açık Erişim
Özet
Calendula officinalis L., (marigold), well known for its medicinal properties, has been extensively studied for its therapeutic properties. Nonetheless, as far as the literature could establish, no study has attempted to comparatively assess the biological (antioxidant and enzyme inhibitory potential) of the flowers, leaves, and roots of C. officinalis extracted using conventional (maceration and Soxhlet extraction (SE)) and non-conventional extraction (homogenizer (HAE) and ultrasound (UAE) assisted extraction) techniques. The detailed phytochemical profile of each extract along with the concentration of specific bioactive compounds has also been established. Total phenolic content was highest for the flower extracts while flavonoid content was highest in the leaf extracts. Phytochemical profiling showed that the extraction method influenced the phytochemical composition of the extract. Nicotiflorin was identified in the flower extracts only while amentoflavone occurred only in the roots, inferring that the occurrence of bioactive compounds varies within a plant. The flower extracts showed highest antioxidant potential while the roots extracts were potent inhibitors of cholinesterase and tyrosinase. This study provides valuable data on the influence of extraction techniques on the recovery of bioactive compounds from plants. In an endeavor to scale-up extraction from plant considering the more efficient extraction method is of paramount importance. Moreover, the study highlighted the necessity to thoroughly examine the biological activities of various parts of a plant obtained via different extraction protocols.
Yazarlar (10)
1
Gunes Ak
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Kouadio Ibrahime Sinan
4
Mohamad Fawzi Mahomoodally
5
Carene Marie Nancy Picot-Allain
6
Oguz Cakir
ORCID: 0000-0002-8006-2054
7
Souheir Bensari
8
Mustafa Abdullah Yılmaz
9
Monica Gallo
10
Domenico Montesano
ORCID: 0000-0002-8857-2091
Anahtar Kelimeler
Cholinesterase
Maceration
Marigold
Tyrosinase
Kurumlar
Dicle Üniversitesi
Diyarbakir Turkey
Duy Tan University
Da Nang Viet Nam
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Napoli Federico II
Naples Italy
Università degli Studi di Perugia
Perugia Italy
Université Constantine 1
Constantine Algeria
University of Mauritius
Reduit Mauritius
Metrikler
39
Atıf
10
Yazar
4
Anahtar Kelime