Phytochemical analysis and biological evaluation of the aerial parts from Symphytum anatolicum Boiss. and Cynoglottis barrelieri (All.) Vural & Kit Tan (Boraginaceae)

Biochemical Systematics and Ecology · Ekim 2020

Makale Bilgileri

DergiBiochemical Systematics and Ecology

Yayın TarihiEkim 2020

Cilt / Sayfa92

DOI10.1016/j.bse.2020.104128

Scopus ID2-s2.0-85089216751

Özet The present study is focused on the phytochemical analysis of the aerial parts of Symphytum anatolicum and Cynoglottis barrelieri (Boraginaceae). Their methanol extracts were subjected to qualitative LC-MS analysis, sixteen secondary metabolites have been identified from S. anatolicum and eighteen from C. barrelieri, respectively. Sixteen among all are phenolic derivatives (phenolic acids and flavonoids) and six belong to pyrrolizidine alkaloids (PAs) in the form of bases and/or N-oxides (PANOs). The observed chemical profiles are discussed chemotaxonomically as both species share the same tribe Boragineae. Caffeic acid and its derivatives together with quercetin- and kaempferol-glucosides were among the common metabolites, as they were identified in both studied plant species. Furthermore, their total phenolic and flavonoid contents were determined. Antioxidant capacity was evaluated by different chemical assays, together with their in vitro enzyme inhibitory properties towards cholinesterases (AChE and BChE), α-amylase and α-glucosidase. The results showed that C. barrelieri exhibited strong antioxidant activity, while S. anatolicum displayed good enzyme inhibitory effects contributing to a very interesting profile for further applications.

Yazarlar (6)

Elisavet Foteini Varvouni

Gokhan Zengin

ORCID: 0000-0001-6548-7823

Konstantia Graikou

ORCID: 0000-0001-6648-558X

Christos Ganos

ORCID: 0000-0002-8217-3444

Tomasz Mroczek

Ioanna Chinou

Anahtar Kelimeler

Biological activities Boraginaceae Cynoglottis barrelieri Phenolic compounds Pyrrolizidine alkaloids Symphytum anatolicum

Kurumlar

Medical University of Lublin

Lublin Poland

National and Kapodistrian University of Athens

Athens Greece

Selçuk Üniversitesi

Selçuklu Turkey

Metrikler

Atıf

Yazar

Anahtar Kelime

Sistemimizdeki Yazarlar

GÖKHAN ZENGİN

PROFESÖR

Hızlı Erişim

DOI ile aç Scopus'ta aç Makaleler listesi

Phytochemical analysis and biological evaluation of the aerial parts from Symphytum anatolicum Boiss. and Cynoglottis barrelieri (All.) Vural &amp; Kit Tan (Boraginaceae)