Scopus
Phytochemical analysis and biological evaluation of Lagochilus species from Uzbekistan
Industrial Crops and Products · Ekim 2020
Makale Bilgileri
DergiIndustrial Crops and Products
Yayın TarihiEkim 2020
Cilt / Sayfa154
Scopus ID2-s2.0-85087282465
Özet
The species of the genus Lagochilus (Lamiaceae) are widespread in Central, South-Central, and Eastern Asia. Some of these species are used for their medicinal and therapeutic effects, in particular as hemostatic, anti-inflammatory and anti-epileptic agents. A new iridoid, glucoside 7- cinnamoyllamalbide, along with known compounds lagochilin, 5-hydroxy-7,4′-dimethoxyflavone, daucosterol, β-sitosterol, 8-acetylharpagide were isolated from L. gypsaceus. The high-performance thin-layer chromatography (HPTLC) method was used to determine the chemical fingerprints of 7 different Lagochilus species (L. acutilobus, L. gypsaceus, L. inebrians, L. olgae, L. proskorjakovii, L. setulosus, L. vvedenskyi). Among the tested species, lagochilin content was highest in the endemic species L. inebrians collected from the Djizzakh region of Uzbekistan. In free radical scavenging and reducing power assays, L. inebrans and L. vvedenskyi exhibited the strongest abilities. Regarding cholinesterases, amylase and glucosidase inhibition abilities of the tested samples, 5-hydroxy-7,4′-dimethoxyflavone was the most active compound.
Yazarlar (9)
1
D. Kh Akramov
2
Markus Bacher
ORCID: 0000-0002-4307-4849
3
Stefan Böhmdorfer
4
Thomas Rosenau
ORCID: 0000-0002-6636-9260
5
Gokhan Zengin
ORCID: 0000-0001-6548-7823
6
Antje Potthast
ORCID: 0000-0003-1981-2271
7
Lutfun Nahar
8
Satyajit D. Sarker
9
Nilufar Z. Mamadalieva
ORCID: 0000-0003-1756-3638
Anahtar Kelimeler
Antioxidant
Enzyme inhibitory activity
HPTLC
Iridoids
Lagochilin
Lagochilus
Kurumlar
BOKU University
Vienna Austria
Liverpool John Moores University
Liverpool United Kingdom
Selçuk Üniversitesi
Selçuklu Turkey
S. Yu. Yunusov Institute of the Chemistry of Plant Substances Uzbekistan Academy of Sciences
Tashkent Uzbekistan
Univerzita Palackého v Olomouci
Olomouc Czech Republic
Metrikler
5
Atıf
9
Yazar
6
Anahtar Kelime