Scopus
YÖKSİS Eşleşti
Chemodiversity and biological activity of essential oils from three species from the Euphorbia genus
Flavour and Fragrance Journal · Ocak 2021
YÖKSİS Kayıtları
Chemodiversity and biological activity of essential oils from three species from the Euphorbia genus
Flavour and Fragrance Journal · 2021 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
Makale Bilgileri
DergiFlavour and Fragrance Journal
Yayın TarihiOcak 2021
Cilt / Sayfa36 · 148-158
Scopus ID2-s2.0-85091607801
Özet
Several studies demonstrated the wide pharmacological properties of extracts and essential oils (EOs) prepared from Euphorbia species. In the present study, the chemical composition and biological activities of EOs from three different Euphorbia species were evaluated using in vitro methods. A total of 29, 33 and 42 constituents were identified in the EOs of E hirta, E convolvuloides and E heterophylla, respectively. The EOs exhibited in vitro radical scavenging potential in the ABTS assay (2.89-21.50 mg/g). Additionally, an inhibitory effect on acetylcholinesterase (4.23-5.12 mg/g) was detected. Besides, remarkable tyrosinase inhibition was reported by the EOs (95.24-113.74 mg/g). Molecular docking was also performed to elucidate the binding interactions between selected EO components and enzymes. Phytol and geranyl-(E)-acetone had a good binding with tyrosinase in the molecular docking. This study highlighted the promising pharmacological profiles of these EOs as natural sources of antioxidants as well as cholinesterase and tyrosinase inhibitors that could be further explored in the management of human ailments in food and pharmaceutical industries.
Yazarlar (12)
1
Kouadio Ibrahime Sinan
2
Ouattara Katinan Etienne
3
Azzurra Stefanucci
4
Adriano Mollica
5
Mohamad Fawzi Mahomoodally
6
Sharmeen Jugreet
7
Gabriele Rocchetti
8
Luigi Lucini
ORCID: 0000-0002-5133-9464
9
Abdurrahman Aktumsek
10
Domenico Montesano
ORCID: 0000-0002-8857-2091
11
Gunes Ak
12
Gokhan Zengin
ORCID: 0000-0001-6548-7823
Anahtar Kelimeler
anti-cholinesterase
anti-tyrosinase
essential oil
Euphorbia
molecular docking
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Università Cattolica del Sacro Cuore, Campus di Piacenza e Cremona
Piacenza Italy
Università degli Studi di Perugia
Perugia Italy
Université de Cocody-Abidjan
Abidjan Cote d'Ivoire
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
University of Mauritius
Reduit Mauritius
Metrikler
15
Atıf
12
Yazar
5
Anahtar Kelime