Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Chemical profiling and biological evaluation of nepeta baytopii extracts and essential oil: An endemic plant from turkey
Plants · Haziran 2021
YÖKSİS Kayıtları
Chemical Profiling and Biological Evaluation of Nepeta baytopii Extracts and Essential Oil: An Endemic Plant from Turkey
Plants · 2021 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
Makale Bilgileri
DergiPlants
Yayın TarihiHaziran 2021
Cilt / Sayfa10
Scopus ID2-s2.0-85107452025
Erişim🔓 Açık Erişim
Özet
Nepeta baytopii is a poorly studied, endemic Nepeta species (Lamiaceae) of Turkey. For the first time, the biological activities (antioxidant, enzyme inhibition, and cytotoxicity properties) of the hexane, ethyl acetate, methanol, water/methanol, and water extracts and essential oil prepared from N. baytopii aerial parts were assessed. Hydro-methanol (41.25 mg gallic acid equivalent (GAE)/g) and water extracts (50.30 mg GAE/g), respectively showed the highest radical scavenging (94.40 and 129.22 mg Trolox equivalent (TE)/g, for 2,2-diphenyl-1-picrylhydrazyl radical and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid radical scavenging assays) and reducing (229.37 and 129.55 mg TE/g, for ferric-reducing antioxidant power and cupric-reducing antioxidant capacity assays) capacities in vitro. An interestingly high inhibition was observed for ethyl acetate extract against butyrylcholinesterase (10.85 mg galantamine equivalent/g). The methanol extract showed high cytotoxicity (31.7%) against HepG2 cells. Caryophyllene oxide was identified in high concentrations in the essential oil (39.3%). Luteolin and apigenin and their derivatives were identified from the methanol and water extracts. The results obtained from this study highlighted that the abundance of highly bioactive compounds from Nepeta baytopii ensures the multiple biological activities of the tested extracts, and this suggests a potential use in the pharmaceutical and nutraceutical fields, and therefore should be investigated further.
Yazarlar (13)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Mohamad Fawzi Mahomoodally
3
Abdurrahman Aktumsek
4
József Jekő
5
Zoltán Cziáky
6
Maria João Rodrigues
7
Luisa Custodio
8
Rıdvan Polat
9
Ugur Cakilcioglu
10
Adnan Ayna
11
Monica Gallo
12
Domenico Montesano
ORCID: 0000-0002-8857-2091
13
Carene Marie Nancy Picot-Allain
Anahtar Kelimeler
Antioxidant
Enzyme inhibition
Nepeta
Phytopharmaceutics
Polyphenols
Kurumlar
Bingöl Üniversitesi
Bingol Turkey
Munzur University
Tunceli Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Universidade do Algarve
Faro Portugal
Università degli Studi di Napoli Federico II
Naples Italy
University of Mauritius
Reduit Mauritius
University of Nyíregyháza
Nyíregyháza Hungary
Metrikler
16
Atıf
13
Yazar
5
Anahtar Kelime