Scopus
🔓 Açık Erişim
The uhplc-qtof-ms phenolic profiling and activity of cydonia oblonga mill. Reveals a promising nutraceutical potential
Foods · Haziran 2021
Makale Bilgileri
DergiFoods
Yayın TarihiHaziran 2021
Cilt / Sayfa10
Scopus ID2-s2.0-85107877039
Erişim🔓 Açık Erişim
Özet
Cydonia oblonga Mill., normally known as the quince fruit, has been widely used in agro-food industries mainly to produce jams and jellies. However, other parts of the plants are still underutilized and not completely assessed for their nutraceutical profile. Therefore, in this work, the polyphenolic profile of C. oblonga was investigated using an untargeted metabolomics approach based on high-resolution mass spectrometry. Several compounds were identified in the different parts of the plants, including flavonoids (i.e., anthocyanins, flavones, flavan-3-ols, and flavonols), phenolic acids (both hydroxycinnamics and hydroxybenzoics), low-molecular-weight phenolics (tyrosol equivalents), lignans, and stilbenes. Overall, C. oblonga leaves showed the highest in vitro antioxidant potential, as revealed by 2,2-difenil-1-picrylhydrazyl (DPPH), 2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), ferric reducing antioxidant power (FRAP), and cupric ion reducing antioxidant capacity (CUPRAC) assays, being 189.5, 285.6, 158.9, and 348.8 mg Trolox Equivalent/g, respectively. The enzymes acetyl-and butyryl-cholinesterases were both inhibited by the different plant parts of C. oblonga, with stems showing the higher inhibitory potential. Interestingly, the fruit extracts were the only parts inhibiting the α-glucosidase, with a value of 1.36 mmol acarbose equivalents (ACAE)/g. On the other hand, strong tyrosinase inhibition was found for stems and leaves, being 72.11 and 68.32 mg Kojic acid Equivalent/g, respectively. Finally, a high number of significant (0.05 < p < 0.01) correlations were outlined between phenolics (mainly anthocyanins, flava-3-ols, and tyrosol equiva-lents) and the different biological assays. Taken together, our findings suggest a potential exploitation of C. oblonga leaves and stems for the food, pharmaceutical, and cosmetic industries.
Yazarlar (7)
1
Leilei Zhang
ORCID: 0000-0002-9278-0459
2
Gabriele Rocchetti
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Gunes Ak
5
Fatema R. Saber
6
Domenico Montesano
ORCID: 0000-0002-8857-2091
7
Luigi Lucini
ORCID: 0000-0002-5133-9464
Anahtar Kelimeler
Antioxidants
Cydonia oblonga
Enzyme inhibitions
Foodomics
Nutraceuticals
Polyphenols
Kurumlar
Faculty of Pharmacy
Cairo Egypt
Selçuk Üniversitesi
Selçuklu Turkey
Università Cattolica del Sacro Cuore, Campus di Piacenza e Cremona
Piacenza Italy
Università degli Studi di Napoli Federico II
Naples Italy
Metrikler
26
Atıf
7
Yazar
6
Anahtar Kelime