Scopus
🔓 Açık Erişim
Bioinformatics accelerates the major tetrad: A real boost for the pharmaceutical industry
International Journal of Molecular Sciences · Haziran 2021
Makale Bilgileri
DergiInternational Journal of Molecular Sciences
Yayın TarihiHaziran 2021
Cilt / Sayfa22
Scopus ID2-s2.0-85107387256
Erişim🔓 Açık Erişim
Özet
With advanced technology and its development, bioinformatics is one of the avant-garde fields that has managed to make amazing progress in the pharmaceutical–medical field by modeling the infrastructural dimensions of healthcare and integrating computing tools in drug innovation, facilitating prevention, detection/more accurate diagnosis, and treatment of disorders, while saving time and money. By association, bioinformatics and pharmacovigilance promoted both sample analyzes and interpretation of drug side effects, also focusing on drug discovery and development (DDD), in which systems biology, a personalized approach, and drug repositioning were considered together with translational medicine. The role of bioinformatics has been highlighted in DDD, proteomics, genetics, modeling, miRNA discovery and assessment, and clinical genome sequencing. The authors have collated significant data from the most known online databases and publishers, also narrowing the diversified applications, in order to target four major areas (tetrad): DDD, antimicrobial research, genomic sequencing, and miRNA research and its significance in the management of current pandemic context. Our analysis aims to provide optimal data in the field by stratification of the information related to the published data in key sectors and to capture the attention of researchers interested in bioinformatics, a field that has succeeded in advancing the healthcare paradigm by introducing developing techniques and multiple database platforms, addressed in the manuscript.
Yazarlar (13)
1
Tapan Behl
2
Ishnoor Kaur
3
Aayush Sehgal
4
Sukhbir Singh
5
Saurabh Bhatia
6
Ahmed Al-Harrasi
7
Gokhan Zengin
ORCID: 0000-0001-6548-7823
8
Elena Emilia Babes
9
Ciprian Brisc
10
Manuela Stoicescu
11
Mirela Marioara Toma
12
Cristian Sava
13
Simona Bungau
Anahtar Kelimeler
Bioinformatics
COVID-19
Microbiology
MicroRNA
Pharmacovigilance
Public health
Kurumlar
AUH-Gurugram
Gurugram India
Chitkara University, Punjab
Rajpura India
Selçuk Üniversitesi
Selçuklu Turkey
Universitatea din Oradea, Facultatea de Medicina
Oradea Romania
University of Nizwa
Nizwa Oman
University of Oradea
Oradea Romania
Metrikler
45
Atıf
13
Yazar
6
Anahtar Kelime