Scopus
🔓 Açık Erişim
Chemical profiling, in vitro biological activities and Pearson correlation between phenolic contents and antioxidant activities of Caragana brachyantha Rech.f
South African Journal of Botany · Ağustos 2021
Makale Bilgileri
DergiSouth African Journal of Botany
Yayın TarihiAğustos 2021
Cilt / Sayfa140 · 189-193
Scopus ID2-s2.0-85105019690
Erişim🔓 Açık Erişim
Özet
Caragana is one of the most important genera of the plant family Fabaceae, and is famous for conventional folklore medicines applications. Therefore, the present investigation was designed to explore therapeutical potentials of various extracts of Caragana brachyantha Rech.f (Hexane, Ethyl acetate, n-Butanol, Methanol, aqueous) through in-vitro biological screening. The UHPLC-MS analysis of the extracts disclosed phytochemical composition and total bioactive contents. Ethyl acetate extract (CBEA) offered the highest phenolic (48.49±1.23 mgGAE/g extract) and flavonoid (16.48±0.26 mgRE/g extract) contents and also exhibited significant antioxidant activities. The observed antioxidant potential was further supported by Pearson correlation studies, which depicted a positive relationship between total phenolic contents (TPC) and total flavonoid contents (TFC). Methanolic extract (CBM) exhibited the highest anti-α-glucosidase activity (2.02±0.02 mmolACAE/g extract) while CBEA was found more active (96.02±3.24 mgKAE/g extract) in tyrosinase inhibition assay. This investigation suggests potential uses of Caragana brachyantha in nutraceutical and pharmaceutical products and thus offers a great industrial application.
Yazarlar (11)
1
Liaquat Ali
2
Saima Khan
3
Mamona Nazir
4
Naheed Raiz
5
Saima Naz
6
Gokhan Zengin
ORCID: 0000-0001-6548-7823
7
Mahreen Mukhtar
8
Shehla Parveen
9
Natasha Shazmeen
10
Muhammad Saleem
11
Rasool Baksh Tareen
Anahtar Kelimeler
Antioxidant
Caragana brachyantha
Flavonoids
Pearson correlation
Phenolics
Tyrosinase
UHPLC-MS analysis
α-Glucosidase
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
The Government Sadiq College Women University Bahawalpur
Bahawalpur Pakistan
The Islamia University of Bahawalpur
Bahawalpur Pakistan
University of Balochistan
Quetta Pakistan
Metrikler
17
Atıf
11
Yazar
8
Anahtar Kelime