Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Uhplc-ms characterization and biological insights of different solvent extracts of two achillea species (A. aleppica and a. santolinoides) from Turkey
Antioxidants · Ağustos 2021
YÖKSİS Kayıtları
UHPLC-MS Characterization and Biological Insights of Different Solvent Extracts of Two Achillea Species (A. aleppica and A. santolinoides) from Turkey
Antioxidants · 2021 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
Makale Bilgileri
DergiAntioxidants
Yayın TarihiAğustos 2021
Cilt / Sayfa10
Scopus ID2-s2.0-85111057172
Erişim🔓 Açık Erişim
Özet
In the current study, Achillea santolinoides and Achillea aleppica aeral parts and root were extracted with ethyl acetate, methanol, and water. Detailed phytochemical profiles were obtained using UHPLC-MS, yielding the identification of hydroxybenzoic and hydroxycinnamic acids, phenolic acid glycosides and sugar esters, acylquinic acids, O-glycosyl flavones and flavonols, and flavonoid aglycons, among others. The antioxidant properties and enzyme inhibitory activities of the extracts were assayed with in vitro tests. The phenolic content of the water extracts was significantly higher as compared to the ethyl acetate and methanol ones. A. aleppica aerial parts methanol extract possessed highest flavonoid content (49.18 mg rutin equivalent/g). Antioxidant properties assess-ment revealed that the methanol extract of A. santolinoides roots actively scavenged DPPH (54.11 mg TE/g) and ABTS radicals (112.53 mg TE/g) and possessed highest reducing potential (183.55 and 129.92 mg TE/g, for CUPRAC and FRAP, respectively). The ethyl acetate extracts of aerial parts and roots of both species showed highest inhibition against BuCHE (6.07–6.76 mg GALAE/g). The ethyl acetate extract of A. santolinoides aerial part showed highest inhibition against tyrosinase (73.00 mg KAE/g). These results showed that the tested Achillea species might represent novel phytotherapeu-tic avenues for the management of Alzheimer’s disease and epidermal hyperpigmentation condi-tions, which are both associated with oxidative stress. This paper could shed light into future potential industrial applications using the tested Achillea species.
Yazarlar (9)
1
Reneta Gevrenova
ORCID: 0000-0002-1254-2419
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Kouadio Ibrahime Sinan
4
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
5
Dimitrina Zheleva-Dimitrova
ORCID: 0000-0002-1952-9903
6
Carene Marie Nancy Picot-Allain
7
Mohamad Fawzi Mahomoodally
8
Muhammad Imran
9
Stefano Dall'Acqua
Anahtar Kelimeler
Biopharmaceuticals
Hyperpigmentation
Medicinal plants
Phenolics
Kurumlar
Medical University of Sofia
Sofia Bulgaria
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Padova
Padua Italy
University of Lahore
Lahore Pakistan
University of Mauritius
Reduit Mauritius
Metrikler
21
Atıf
9
Yazar
4
Anahtar Kelime