Scopus
🔓 Açık Erişim
Influence of the post‐harvest storage time on the multi‐biological potential, phenolic and pyrrolizidine alkaloid content of comfrey (Symphytum officinale l.) roots collected from different european regions
Plants · Eylül 2021
Makale Bilgileri
DergiPlants
Yayın TarihiEylül 2021
Cilt / Sayfa10
Scopus ID2-s2.0-85114089750
Erişim🔓 Açık Erişim
Özet
Comfrey (Symphytum officinale L.) roots are well‐known bioactive ingredients included in various cosmeceutical and pharmaceutical preparations. In this study, the influence of the post-harvest storage on the chemico‐biological potential of roots collected from different European regions and stored for up to six months was investigated. Total phenolic content (TPC) and total phenolic acid content (TPAC) were spectrophotometrically estimated, whereas the levels of individual phenolic and pyrrolizidine alkaloidal markers were determined by HPLC‐DAD and HPLC‐MS/MS, respectively. The changes in the biological potential was tracked via antioxidant (DPPH, ABTS, CUPRAC, and FRAP) and anti‐enzymatic (cholinesterase, tyrosinase, glucosidase, and amylase) assays. TPC and TPAC varied from 6.48–16.57 mg GAE/g d.w. root and from 2.67– 9.03 mg CAE/g, respectively. The concentration of the four phenolics (rosmarinic acid, globoidnan A, globoidnan B, rabdosiin) and six pyrrolizidine alkaloids generally showed maximum values at 1–3 months, after which their levels significantly decreased. With respect to the bioassays, the samples showed a wide range of antioxidant and anti‐enzymatic effects; however, a direct storage time–bioactivity relationship was not observed. Similar conclusions were also revealed by the multivariate and correlation analyses. Our study could improve the current knowledge of the shelf-life properties of comfrey‐based products and enhance their industrial exploitation.
Yazarlar (9)
1
Adriana Trifan
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Kouadio Ibrahime Sinan
4
Nils Esslinger
5
Andreas Grubelnik
6
Evelyn Wolfram
7
Krystyna Skalicka-Wozniak
8
Mirjana Minceva
ORCID: 0000-0001-9820-7410
9
Simon Vlad Luca
ORCID: 0000-0001-8785-249X
Anahtar Kelimeler
Antioxidant
Enzyme inhibition
Globoidnan A
Rosmarinic acid
Storage
Symphytum
Kurumlar
Alpinamed AG
Freidorf Switzerland
Medical University of Lublin
Lublin Poland
Selçuk Üniversitesi
Selçuklu Turkey
Technische Universität München
Munich Germany
Universitatea de Medicina si Farmacie Grigore T. Popa din Iasi
Iasi Romania
ZHAW Zurich University of Applied Sciences
Winterthur Switzerland
Metrikler
6
Atıf
9
Yazar
6
Anahtar Kelime