Scopus
🔓 Açık Erişim
Anticancer and anti-inflammatory effects of tomentosin: Cellular and molecular mechanisms
Separations · Kasım 2021
Makale Bilgileri
DergiSeparations
Yayın TarihiKasım 2021
Cilt / Sayfa8
Scopus ID2-s2.0-85119036547
Erişim🔓 Açık Erişim
Özet
Tomentosin is a natural compound known for its presence in some medicinal plants of the Asteraceae family such as Inula viscosa. Recent studies have highlighted its anticancer and anti-inflammatory properties. Its anticancer mechanisms are unique and act at different levels ranging from cellular organization to molecular transcriptional factors and epigenetic modifications. Tomentosin’s possession of the modulatory effect on telomerase expression on tumor cell lines has captured the interest of researchers and spurred a more robust study on its anticancer effect. Since inflammation has a close link with cancer disease, this natural compound appears to be a potential cancer-fighting drug. Indeed, its recently demonstrated anti-inflammatory action can be considered as a starting point for its evaluation as an anticancer chemo-preventive agent.
Yazarlar (8)
1
Nasreddine El Omari
2
Naoual El Menyiy
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Bey Hing Goh
5
Monica Gallo
6
Domenico Montesano
ORCID: 0000-0002-8857-2091
7
Daniele Naviglio
ORCID: 0000-0001-5191-7669
8
Abdelhakim Bouyahya
ORCID: 0000-0001-9317-1631
Anahtar Kelimeler
Apoptosis
Cancer
Inflammation
NF-κB
Telomerase
Tomentosin
Kurumlar
College of Pharmaceutical Sciences, Zhejiang University
Hangzhou China
Faculté de Médecine et de Pharmacie de Rabat
Rabat Morocco
Faculté des Sciences Rabat
Rabat Morocco
Monash University Malaysia
Bandar Sunway Malaysia
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Napoli Federico II
Naples Italy
Université Sidi Mohamed Ben Abdellah
Fez Morocco
Metrikler
17
Atıf
8
Yazar
6
Anahtar Kelime