Scopus
Sources, health benefits, and biological properties of zeaxanthin
Trends in Food Science and Technology · Aralık 2021
Makale Bilgileri
DergiTrends in Food Science and Technology
Yayın TarihiAralık 2021
Cilt / Sayfa118 · 519-538
Scopus ID2-s2.0-85118201652
Özet
Background: Zeaxanthin is a carotenoid pigment found in several fruits and vegetables. Belonging to the xanthophyll family, it is widely present in human and some animals skin and eyes, performing important physiological functions due to its antioxidant and anti-inflammatory effects. Several studies have explored its health benefits against important disorders such as neurological diseases, allergies, and cancer. Scope and approach: The aim of this study we to explore the sources, health benefits, and biological properties of zeaxanthin and analyzes its drug interaction with β-carotene. Key findings and conclusion: Severela vegetable sources in particularly fruits parts contains zeaxanthin. Biological investigations showed that zeaxanthin has been found to exhibit a protective effect against excessive light and oxidative stress side effects, preventing the development of several neurological, skin, and eye disorders. It exhibits also antioxidant, antiparasitic, anthelmintic activity, and antiosteoporosis effects. Zeaxanthin can also play a role in the inflammatory response, contributing to the treatment or prevention of diseases like allergies and AIDS. Additionally, zeaxanthin can exhibit anticancer, anti-osteoporotic, and ophthalmologic effects. These different properties are mediated by diffetent cellular and molecular mechanisms exhibited by zeaxanthin such as its activation and/or blocker of cell receptors, its actions on signaling pathways, and also its effects on gene expression. Moreover, the safety as a dietary supplement has also been confirmed and its interaction with other carotenoids, such as β-carotene, has been studied and validated in pharmacokinetic investigations. However, further investigations are needed to explore the full potential of zeaxanthin and to elucidate more its molecular pharmacodynamic actions behind its effects on human health, and to investigate also its clinical applications.
Yazarlar (14)
1
Abdelhakim Bouyahya
ORCID: 0000-0001-9317-1631
2
Nasreddine El Omari
3
Meryem Hakkur
4
Naoufal El Hachlafi
ORCID: 0000-0003-0768-5914
5
Saoulajan Charfi
6
Abdelaali Balahbib
7
Fatima Ezzahrae Guaouguaou
8
Maksim Rebezov
9
Nikolai Maksimiuk
ORCID: 0000-0001-6634-7638
10
Mohammad Ali Shariati
ORCID: 0000-0001-9376-5771
11
Gokhan Zengin
ORCID: 0000-0001-6548-7823
12
Naoual El Menyiy
13
Imane Chamkhi
14
Saad Bakrim
Anahtar Kelimeler
Allergies
Anticancer
Human health
Neurological diseases
Zeaxanthin
Kurumlar
Ecole Normale Supérieure de Rabat
Rabat Morocco
Faculté de Médecine et de Pharmacie de Rabat
Rabat Morocco
Faculté des Sciences Rabat
Rabat Morocco
Institut Scientifique
Rabat Morocco
Mohammed VI Polytechnic University
Ben Guerir Morocco
Moscow State University of Technologies and Management
Moscow Russian Federation
Prokhorov General Physics Institute of the Russian Academy of Sciences
Moscow Russian Federation
Selçuk Üniversitesi
Selçuklu Turkey
Université Abdelmalek Essaadi
Tetouan Morocco
Université Ibn Zohr
Agadir Morocco
Université Sidi Mohamed Ben Abdellah
Fez Morocco
V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences
Moscow Russian Federation
Yaroslav-the-Wise Novgorod State University
Veliky Novgorod Russian Federation
Metrikler
44
Atıf
14
Yazar
5
Anahtar Kelime