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Comprehensive approaches on chemical composition and biological properties of Daphne pontica L. extracts

Plant Biosystems · Ocak 2022

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YÖKSİS Kayıtları
Comprehensive approaches on chemical composition and biological properties of Daphne pontica L. extracts
PLANT BIOSYSTEMS · 2022 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Comprehensive approaches on chemical composition and biological properties of Daphne pontica L. extracts
PLANT BIOSYSTEMS · 2022 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 13 kaydı bulundu.

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Comprehensive approaches on chemical composition and biological properties of Daphne pontica L. extracts
2022 ISSN: 1126-3504 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
Comprehensive approaches on chemical composition and biological properties of Daphne pontica L. extracts
2022 ISSN: 1126-3504 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
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Makale Bilgileri

ISSN11263504
Yayın TarihiOcak 2022
Cilt / Sayfa156 · 116-129
Özet The genus Daphne presents great interest as a valuable source of natural agents in traditional medicine of various countries, including Turkey. In the current work, we investigated the phytochemical composition and biological properties of Daphne pontica L. extracts. Methanol extracts of roots, stems and leaves were prepared. The chemical characterization was performed by HPLC-ESI-MSn, observing that flavonoids and phenolic acids were the main compounds. Biological properties were studied in terms of antimicrobial, DNA protection, anticancer, and enzyme inhibitory properties (cholinesterases, tyrosinase, amylase and glucosidase). Methanol extracts of roots, leaves, and stems of D. pontica had antimicrobial effects against a broad range of bacteria. In addition, methanol extract of roots of D. pontica exhibited a promising anticancer activity that was shown to be dose- and time-dependent for HeLa cells with an IC50 value of 203.9 μg/mL. Generally, the leaf extracts exhibited the best enzyme inhibitory properties on the tested enzymes. According to our results, D. pontica might be regarded as a valuable source of natural agents to combat cancer, infectious diseases, and metabolic diseases.

Yazarlar (7)

1
Yasemin Celik Altunoglu
2
Tevfik Hasan Can
ORCID: 0000-0001-8125-4093
3
Enis Fuat Tüfekci
4
Bahattin Deniz Altunoglu
ORCID: 0000-0001-7609-1883
5
Mehmet Cengiz Baloglu
6
E. J. Llorent-Martínez
7
Gokhan Zengin
ORCID: 0000-0001-6548-7823

Anahtar Kelimeler

anticancer antimicrobial Daphne pontica L enzymes phenolics

Kurumlar

Kastamonu University
Kastamonu Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Universidad de Jaén
Jaen Spain
University of Florida Institute of Food and Agricultural Sciences
Gainesville United States
Scimago Dergi (ISSN Eşleşmesi)
Plant Biosystems
Q2
SJR Skoru0,474
H-Index68
YayıncıSpringer International Publishing
ÜlkeUnited Kingdom
Ecology, Evolution, Behavior and Systematics (Q2)
Plant Science (Q2)
Dergi sayfasına git

Metrikler

7
Atıf
7
Yazar
5
Anahtar Kelime

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