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Bioactive constituents, antioxidant effects and enzyme inhibitory properties of two Onosma species (Onosma trapezuntea and O. rigidum)

South African Journal of Botany · Mart 2022

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YÖKSİS Kayıtları
Bioactive constituents, antioxidant effects and enzyme inhibitory properties of two Onosma species (Onosma trapezuntea and O. rigidum)
South African Journal of Botany · 2021 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

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Makale Bilgileri

Dergi South African Journal of Botany
ISSN02546299
Yayın TarihiMart 2022
Cilt / Sayfa145 · 142-148
DOI10.1016/j.sajb.2021.09.036
Scopus ID2-s2.0-85116864767
Erişim🔓 Açık Erişim
Özet The genus Onosma is the biggest genus in the family Boraginaceae and its members are widely used for traditional purposes in several countries folk medicine. In the current work, two Onosma (O. trapezuntea and O. rigidum) species were examined for biological properties and chemical characterization. To evaluate biological properties, antioxidant and enzyme inhibitory assays were performed. Antioxidant assays included free radical scavenging (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH)), reducing power (cupric reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP)), metal chelating and phosphomolybdenum. Enzyme inhibitory were assessed against cholinesterase, tyrosinase, α-amylase and α-glucosidase. Total phenolic and flavonoid contents in O. trapezuntea were higher than those of O. rigidum. Liquid chromatography-mass spectrometry (LC-MS) analysis revealed that chlorogenic acid, rosmarinic acid and hyperoside were dominant compounds in the chemical profiles of the tested Onosma extracts. Generally, O. trapezuntea exhibited stronger antioxidant abilities than O. rigidum. However, the best chelating ability was recorded in O. rigidum. In addition, O. rigidum was more active on cholinesterase and α-glucosidase when compared with O. trapezuntea. The tested extracts exhibited similar tyrosinase inhibitory potentials. Consequently, our findings suggested that the tested Onosma species could be presented as valuable sources of natural ingredients such as antioxidant and enzyme inhibitors.

Yazarlar (3)

1
Bulent Kirkan
2
Cengiz Sarikurkcu
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823

Anahtar Kelimeler

Bioactive agents Cholinesterase Free radicals Onosma Rosmarinic acid

Kurumlar

Afyonkarahisar Health Sciences University
Afyonkarahisar Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Süleyman Demirel Üniversitesi
Isparta Turkey
Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Dergi sayfasına git

Metrikler

12
Atıf
3
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

GZ
GÖKHAN ZENGİN
Prof. Dr.

Hızlı Erişim

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