Scopus
🔓 Açık Erişim
Natural Sources and Pharmacological Properties of Pinosylvin
Plants · Haziran 2022
Makale Bilgileri
DergiPlants
Yayın TarihiHaziran 2022
Cilt / Sayfa11
Scopus ID2-s2.0-85131592239
Erişim🔓 Açık Erişim
Özet
Pinosylvin (3,5-dihydroxy-trans-stilbene), a natural pre-infectious stilbenoid toxin, is a terpenoid polyphenol compound principally found in the Vitaceae family in the heartwood of Pinus spp. (e.g., Pinus sylvestris) and in pine leaf (Pinus densiflora). It provides defense mechanisms against pathogens and insects for many plants. Stilbenoids are mostly found in berries and fruits but can also be found in other types of plants, such as mosses and ferns. This review outlined prior research on pinosylvin, including its sources, the technologies used for its extraction, purification, identification, and characterization, its biological and pharmacological properties, and its toxicity. The collected data on pinosylvin was managed using different scientific research databases such as PubMed, SciFinder, SpringerLink, ScienceDirect, Wiley Online, Google Scholar, Web of Science, and Scopus. In this study, the findings focused on pinosylvin to understand its pharmacological and biological activities as well as its chemical characterization to explore its potential therapeutic approaches for the development of novel drugs. This analysis demonstrated that pinosylvin has beneficial effects for various therapeutic purposes such as antifungal, antibacterial, anticancer, anti-inflammatory, antioxidant, neuroprotective, anti-allergic, and other biological functions. It has shown numerous and diverse actions through its ability to block, interfere, and/or stimulate the major cellular targets responsible for several disorders.
Yazarlar (13)
1
Saad Bakrim
2
Hamza Machate
3
Taoufiq Benali
4
Nargis Sahib
5
Imane Jouadi
ORCID: 0000-0003-0753-1667
6
Nasreddine El Omari
7
Sara Aboulaghras
8
Sneh Punia Bangar
ORCID: 0000-0002-8675-6399
9
José M. Lorenzo
ORCID: 0000-0002-7725-9294
10
Gokhan Zengin
ORCID: 0000-0001-6548-7823
11
Domenico Montesano
ORCID: 0000-0002-8857-2091
12
Monica Gallo
13
Abdelhakim Bouyahya
ORCID: 0000-0001-9317-1631
Anahtar Kelimeler
antimicrobial
cancer
pharmacological property
pinosylvin
signaling pathway
Kurumlar
Clemson University
Clemson United States
Faculté de Médecine et de Pharmacie de Rabat
Rabat Morocco
Faculté des Sciences Rabat
Rabat Morocco
Faculty of Science, Ibn Tofail University
Kenitra Morocco
Fundación Centro Tecnolóxico da Carne
San Cibrao das Vinas Spain
Selçuk Üniversitesi
Selçuklu Turkey
Universidade de Vigo
Vigo Spain
Università degli Studi di Napoli Federico II
Naples Italy
Université Cadi Ayyad
Marakech Morocco
Université Ibn Zohr
Agadir Morocco
Université Mohammed Premier Oujda
Oujda Morocco
Université Sidi Mohamed Ben Abdellah
Fez Morocco
Metrikler
28
Atıf
13
Yazar
5
Anahtar Kelime