Scopus
YÖKSİS Eşleşti
The characterization of phenolic compounds via LC-ESI-MS/MS, antioxidant, enzyme inhibitory activities of Salvia absconditiflora, Salvia sclarea, and Salvia palaestina: A comparative analysis
South African Journal of Botany · Kasım 2022
YÖKSİS Kayıtları
The characterization of phenolic compounds via LC-ESI-MS/MS, antioxidant, enzyme inhibitory activities of Salvia absconditiflora, Salvia sclarea, and Salvia palaestina: A comparative analysis
South African Journal of Botany · 2022 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiSouth African Journal of Botany
Yayın TarihiKasım 2022
Cilt / Sayfa150 · 313-322
Scopus ID2-s2.0-85134893500
Özet
Salvia L. genus, one of the medicinal and aromatic plants belonging to the Lamiaceae family, is represented by many endemic species in temperate regions worldwide. The Salvia species have plenty of usages in traditional medicine, important pharmacological effects and economic value. In this context, this study was conducted to evaluate the chemical profile and potential bioactivity of ethyl acetate extracts from 3 different Salvia species; Salvia absconditiflora (Salvia cryptantha- an endemic species), S. sclarea and S. palaestina collected from different localities in Anatolia. Total phenolic-flavonoid contents, antioxidant properties and enzyme inhibition experiments were investigated in tested Salvia species. The phenolic profiles were also determined by liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The analysis revealed the presence of phenolic compounds in ethyl acetate extracts such as cynaroside, rosmarinic acid, cosmosiin, luteolin, apigenin and acacetin. The highest level of phenolic components was detected in S. absconditiflora with 74.16 mg GAE/g. The best radical scavenging and reducing abilities were found in S. absconditiflora (DPPH: 251.39 mg TE/g; ABTS: 340.16 mg TE/g; CUPRAC: 496.20 mg TE/g; FRAP: 322.94 mg TE/g). Moreover, the inhibition of AChE, BChE, and α-amylase has also been studied. The most potent AChE inhibitory ability was recorded in S. sclarea (4.00 mg GALAE/g), followed by S. palaestina (3.38 mg GALAE/g) and S. absconditiflora (3.01 mg GALAE/g). The extracts exhibited similar amylase inhibitory effects. These results reveal that Salvia species [S. absconditiflora (S. cryptantha), S. sclarea and S. palaestina] confirming their potential can be rich sources of promising bioactive compounds as a starting point for further analysis. In addition, it is thought that this study may be the new report for the construction of helpful databases in terms of shedding light on future research and researchers with the valuable information obtained about these economically important Salvia species.
Yazarlar (5)
1
Alev Onder
ORCID: 0000-0002-9088-1045
2
Mehmet Necat Izgi
3
Ahsen Sevde Cinar
4
Gokhan Zengin
ORCID: 0000-0001-6548-7823
5
Mustafa Abdullah Yılmaz
Anahtar Kelimeler
Antioxidant
Enzyme inhibitory activity
LC-MS/MS
Phenolics
S. absconditiflora
Salvia
S. palaestina
S. sclarea
Kurumlar
Ankara Üniversitesi
Ankara Turkey
Dicle Üniversitesi
Diyarbakir Turkey
Lokman Hekim Üniversitesi
Ankara Turkey
Mardin Artuklu University
Mardin Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
12
Atıf
5
Yazar
8
Anahtar Kelime