Scopus
🔓 Açık Erişim
Untargeted Metabolomics Used to Describe the Chemical Composition, Antioxidant and Antimicrobial Effects of Extracts from Pleurotus spp. Mycelium Grown in Different Culture Media
Antibiotics · Kasım 2022
Makale Bilgileri
DergiAntibiotics
Yayın TarihiKasım 2022
Cilt / Sayfa11
Scopus ID2-s2.0-85141694711
Erişim🔓 Açık Erişim
Özet
Pleurotus species isolated in vitro were studied to determine the effect of different media on their production of secondary metabolites, antimicrobial, and antioxidant activity. The different metabolites among Pleurotus samples covered a total of 58 pathways. Comparisons were made between the metabolic profiles of Pleurotus spp. mycelia grown in two substrates: Potato-dextrose-agar-PDA, used as control (S1), and PDA enriched with 0.5 % of wheat straw (S2). The main finding was that the metabolic pathways are strongly influenced by the chemical composition of the growth substrate. The antibacterial effects were particularly evident against Escherichia coli, whereas Arthroderma curreyi (CCF 5207) and Trichophyton rubrum (CCF 4933) were the dermatophytes more sensitive to the mushroom extracts. The present study supports more in-depth investigations, aimed at evaluating the influence of growth substrate on Pleurotus spp. antimicrobial and antioxidant properties.
Yazarlar (21)
1
Giancarlo Angeles Flores
ORCID: 0000-0001-6651-9794
2
Carolina Elena Girometta
ORCID: 0000-0002-2583-4664
3
Gaia Cusumano
4
Paola Angelini
ORCID: 0000-0002-6862-1079
5
Bruno Tirillini
ORCID: 0000-0001-7581-8614
6
Federica Ianni
ORCID: 0000-0003-4293-3100
7
Francesca Blasi
ORCID: 0000-0002-1902-2686
8
Lina Cossignani
ORCID: 0000-0003-3433-604X
9
Roberto Maria Pellegrino
ORCID: 0000-0001-5594-383X
10
Carla Emiliani
11
Roberto Venanzoni
ORCID: 0000-0002-7768-0468
12
Giuseppe Venturella
ORCID: 0000-0001-8646-5594
13
Pasqualina Colasuonno
14
Fortunato Cirlincione
ORCID: 0000-0003-0923-7488
15
Maria Letizia Gargano
16
Gokhan Zengin
ORCID: 0000-0001-6548-7823
17
Alessandra Acquaviva
18
Simonetta Cristina Di Simone
ORCID: 0000-0001-5041-3848
19
Giustino Orlando
20
Luigi Menghini
ORCID: 0000-0002-7346-7395
21
Claudio Ferrante
Anahtar Kelimeler
antimicrobial effect
metabolomics
phenolic compounds
Pleurotus species
Kurumlar
Azienda Ospedaliera di Perugia
Perugia Italy
Selçuk Üniversitesi
Selçuklu Turkey
Università degli studi di Bari Aldo Moro
Bari Italy
Università degli Studi di Palermo
Palermo Italy
Università degli Studi di Pavia
Pavia Italy
Università degli Studi di Perugia
Perugia Italy
Università degli Studi di Urbino Carlo Bo
Urbino Italy
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
Metrikler
8
Atıf
21
Yazar
4
Anahtar Kelime