Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Phytochemical Profile and Biological Activities of Different Extracts of Three Parts of Paliurus spina-christi: A Linkage between Structure and Ability
Antioxidants · Şubat 2023
YÖKSİS Kayıtları
Phytochemical profile and biological activities of different extracts of three parts of Paliurus spina-christi: a linkage between structure and ability
Antioxidants · 2023 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
Makale Bilgileri
DergiAntioxidants
Yayın TarihiŞubat 2023
Cilt / Sayfa12
Scopus ID2-s2.0-85149246417
Erişim🔓 Açık Erişim
Özet
Paliurus spina-christi Mill., a member of the Rhamnaceae family, is a traditionally used medicinal plant in the management of a panoply of human ailments. The current research focused on its phytochemical profile and biological properties evaluated by its antioxidant and enzyme inhibitory properties. The methanol extract was found to be the most effective antioxidant as evidenced by its DPPH and ABTS scavenging activities, cupric and ferric reducing power (CUPRAC and FRAP), and high activity in phosphomolybdenum (PBD) assay, and also displayed the highest anti-tyrosinase activity. The n-hexane extract was the most effective AChE inhibitor (8.89 ± 0.08 mg GALAE/g) followed by the methanol (8.64 ± 0.01 mg GALAE/g) while the latter showed the highest BChE inhibition (2.50 ± 0.05 mg GALAE/g). Among the different solvent extracts of the stem, the methanolic extract showed highest antioxidant activity in the following assays: DPPH (909.88 ± 4.25 mg TE/g), ABTS (3358.33 ± 51.14 mg TE/g), CUPRAC (781.88 ± 16.37 mg TE/g), FRAP (996.70 ± 47.28 mg TE/g), and PBD (4.96 ± 0.26 mmol TE/g), while the dichloromethane extract showed the highest MCA (28.80 ± 0.32 mg EDTAE/g). The methanol extracts revealed the highest TPC and TFC among the different solvents used, and as for plant part, the stem extracts had the highest TPC ranging from 22.36 ± 0.26 to 121.78 ± 1.41 (mg GAE/g), while the leaf extracts showed the highest TFC ranging from 8.43 ± 0.03 to 75.36 ± 0.92 (mg RE/g). Our findings tend to provide additional scientific evidence on the biological and chemical activities of P. spina-christi, which may serve as a source of naturally occurring bioactive chemicals with potential biomedical applications.
Yazarlar (11)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Álvaro Fernández-Ochoa
3
María de la Luz Cádiz-Gurrea
4
Francisco Javier Leyva-Jiménez
5
Antonio Segura-Carretero
ORCID: 0000-0002-5564-5338
6
Fevzi Elbasan
7
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
8
Sumira Malik
ORCID: 0000-0001-5077-1493
9
Asaad Khalid
10
Ashraf N. Abdalla
11
Mohamad Fawzi Mahomoodally
Anahtar Kelimeler
antioxidant
enzyme inhibition
phytochemicals
P. spina-christi
Kurumlar
Amity University Jharkhand
Ranchi India
Jazan University
Jizan Saudi Arabia
National Center for Research Sudan
Khartoum Sudan
North-West University
Potchefstroom South Africa
Saveetha Dental College And Hospitals
Chennai India
Selçuk Üniversitesi
Selçuklu Turkey
Umm Al-Qura University
Makkah Saudi Arabia
Universidad de Castilla-La Mancha
Ciudad Real Spain
Universidad de Granada, Facultad de Ciencias
Granada Spain
University of Mauritius
Reduit Mauritius
Metrikler
5
Atıf
11
Yazar
4
Anahtar Kelime