Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Chemical Characterization and Multidirectional Biological Effects of Different Solvent Extracts of Arum elongatum: in Vitro and in Silico Approaches
Chemistry and Biodiversity · Nisan 2023
YÖKSİS Kayıtları
Chemical Characterization and Multidirectional Biological Effects of Different Solvent Extracts of Arum elongatum: in vitro and in silico Approaches
Chemistry & Biodiversity · 2023 SCI-Expanded
Prof. Dr. EVREN YILDIZTUGAY →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Metabolite Profiling by Hyphenated Liquid Chromatographic Mass Spectrometric Technique (HPLC‐DAD‐ESI‐Q‐TOF‐MS/MS) and Neurobiological Potential of iHaplophyllum sahinii/i and iH. vulcanicum/i Extracts/title
2019 ISSN: 1612-1872 SCI-Expanded
Prof. Dr. OSMAN TUGAY →
Protective Effect of Nigella sativa and Nigella damascena Fixed Oils Against Aflatoxin Induced Mutagenicity in the Classical and Modified Ames Test
2021 ISSN: 1612-1872 SCI-Expanded Q3
Dr. Öğr. Üyesi İREM AYRAN ÇOLAK →
Protective Effect of Nigella sativa and Nigella damascena Fixed Oils Against Aflatoxin Induced Mutagenicity in the Classical and Modified Ames Test
2021 ISSN: 1612-1872 SCI-Expanded Q3
Prof. Dr. YÜKSEL KAN →
A ProspectiveofMultipleBiopharmaceuticalActivitiesofProcyanidins-RichUapacatogoensisPaxExtracts:HPLC-ESI-TOF-MSCoupledwithBioinformaticsAnalysis
2021 ISSN: 1612-1872 SCI-Expanded Q3
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
A comparative study of chemical profiling and biological effects of Doronicum orientale extracts
2022 ISSN: 1612-1872 SCI-Expanded Q3
Prof. Dr. EVREN YILDIZTUGAY →
Synthesis and Characterization of Copper\u2010Nanoflowers with the Utilization of Medicinal Plant Extracts for Enhanced Various Enzyme Inhibitory Activities
2022 ISSN: 1612-1872 SCI-Expanded Q3
Prof. Dr. NURANİYE ERUYGUR →
Synthesis and Characterization of Copper‐Nanoflowers with the Utilization of Medicinal Plant Extracts for Enhanced Various Enzyme Inhibitory Activities
2022 ISSN: 1612-1872 SCI-Expanded Q3
Dr. Öğr. Üyesi CEYLAN DÖNMEZ →
Metabolite Profiling by Hyphenated Liquid Chromatographic Mass Spectrometric Technique (HPLC‐DAD‐ESI‐Q‐TOF‐MS/MS) and Neurobiological Potential ofHaplophyllum sahiniiandH. vulcanicumExtracts
2019 ISSN: 1612-1872 SSCI
Arş. Gör. ESENGÜL ÖZKAYMAKOĞLU →
Synthesis and Characterization of Copper‐Nanoflowers with the Utilization of Medicinal Plant Extracts for Enhanced Various Enzyme Inhibitory Activities
2022 ISSN: 1612-1872 SCI-Expanded Q3
Doç. Dr. FATMA AYAZ →
Cytotoxic and Antimigratory Activity of Retrochalcones from Glycyrrhiza echinata L. on Human Cancer Cells
2022 ISSN: 1612-1872 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Protective Effect of Nigella sativa and Nigella damascena Fixed Oils Against Aflatoxin Induced Mutagenicity in the Classical and Modified Ames Test
2021 ISSN: 1612-1872 SCI Q3
Prof. Dr. YÜKSEL KAN →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
2023 ISSN: 1612-1872 SCI-Expanded Q3
Prof. Dr. MEHMET TUZCU →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
2023 ISSN: 1612-1872 SCI-Expanded Q3
Dr. Öğr. Üyesi ŞEYMA TETİK RAMA →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
2023 ISSN: 1612-1872 SCI-Expanded Q3
Arş. Gör. TUĞSEN BÜYÜKYILDIRIM →
Cytotoxic and Antimigratory Activity of Retrochalcones from Glycyrrhiza echinata L. on Human Cancer Cells
2023 ISSN: 1612-1872 SCI
Prof. Dr. YÜKSEL KAN →
Antioxidant and Enzyme Inhibitory Activities of Rhoifolin Flavonoid: In Vitro and in Silico Studies
2023 ISSN: 1612-1872 SCI-Expanded Q3
Prof. Dr. GÖKHAN ZENGİN →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
2023 ISSN: 1612-1872 SCI-Expanded Q3
Doç. Dr. FATMA AYAZ →
Enzyme Inhibitory and Antioxidant Potential with Phytochemical Analysis of Satureja hasturkii H.Duman & Dirmenci: A New Record From Türkiye
2025 ISSN: 1612-1872 SCI-Expanded
Arş. Gör. TUĞSEN BÜYÜKYILDIRIM →
Screening for Antioxidant Effects and Chemical Profiles of Different Extracts of Rheum ribes Parts
2025 ISSN: 1612-1872 SCI-Expanded
Prof. Dr. ATİLLA ARSLAN →
Screening for Antioxidant Effects and Chemical Profiles of Different Extracts of Rheum ribes Parts
2025 ISSN: 1612-1872 SCI-Expanded Q3
Prof. Dr. EMİNE ARSLAN →
Makale Bilgileri
ISSN16121872
Yayın TarihiNisan 2023
Cilt / Sayfa20
Scopus ID2-s2.0-85150664088
Erişim🔓 Açık Erişim
Özet
Arum elongatum (Araceae) is widely used traditionally for the treatment of abdominal pain, arterial hypertension, diabetes mellitus, rheumatism and hemorrhoids. This study investigated the antioxidant properties, individual phenolic compounds, total phenolic and total flavonoid contents (HPLC/MS analysis), reducing power and metal chelating effects of four extracts obtained from A. elongatum (ethyl acetate (EA), methanol (MeOH), methanol/water (MeOH/water) and infusion). The inhibitory activity of the extracts were also determined against acetylcholinesterase, butyrylcholinesterase, tyrosinase, amylase and glucosidase enzymes. The MeOH/water extracts contained the highest amount of phenolic contents (28.85 mg GAE/g) while the highest total flavonoid content was obtained with MeOH extract (36.77 mg RE/g). MeOH/water demonstrated highest antioxidant activity against DPPH⋅ radical at 38.90 mg Trolox equivalent per gram. The infusion extract was the most active against ABTS+⋅ (133.08 mg TE/g). MeOH/water extract showed the highest reducing abilities with the CUPRAC value of 102.22 mg TE/g and the FRAP value of 68.50 mg TE/g. A strong metal chelating effect was observed with MeOH/water extract (35.72 mg EDTAE/g). The PBD values of the extracts ranged from 1.01 to 2.17 mmol TE/g. EA extract displayed the highest inhibitory activity against AChE (2.32 mg GALAE/g), BChE (3.80 mg GALAE/g), α-amylase (0.56 mmol ACAE/g) and α-glucosidase (9.16 mmol ACAE/g) enzymes. Infusion extract was the most active against tyrosinase enzyme with a value of 83.33 mg KAE/g. A total of 28 compounds were identified from the different extracts. The compounds present in the highest concentration were chlorogenic acids, 4-hydroxybenzoic acid, caffeic acid, p-coumaric acid, ferulic acid, isoquercitrin, delphindin 3,5-diglucoside, kaempferol-3-glucoside and hyperoside. The biological activities of A. elongatum extracts could be due to the presence of compounds such as gallic acid, chlorogenic acids, ellagic acid, epicatechin, catechin, kaempferol, 4-hydroxybenzoic acid, caffeic acid, p-coumaric acid, ferulic acid, quercetin, isoquercitrin, and hyperoside. Extracts of A. elongatum showed promising biological activities which warrants further investigations in an endeavor to develop biopharmaceuticals.
Yazarlar (13)
1
Mohamad Fawzi Mahomoodally
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Seebaluck Sandoram Roumita
4
Giovanni Caprioli
ORCID: 0000-0002-5530-877X
5
Ahmed M. Mustafa
6
Diletta Piatti
ORCID: 0009-0001-9590-5560
7
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
8
Gunes Ak
9
Ayşe Esra Karadağ
10
Asaad Khalid
11
Ashraf N. Abdalla
12
Abdullahi Ibrahim Uba
13
Fatih Demirci
Anahtar Kelimeler
Arum
bioactive agent
natural enzyme inhibitors
phenolic composition
Kurumlar
Anadolu Üniversitesi
Eskisehir Turkey
İstanbul Arel Üniversitesi
Istanbul Turkey
İstanbul Medipol Üniversitesi
Istanbul Turkey
Jazan University
Jizan Saudi Arabia
National Center for Research Sudan
Khartoum Sudan
North-West University
Potchefstroom South Africa
Saveetha Dental College And Hospitals
Chennai India
Selçuk Üniversitesi
Selçuklu Turkey
Umm Al-Qura University
Makkah Saudi Arabia
Università degli Studi di Camerino
Camerino Italy
University of Mauritius
Reduit Mauritius
Scimago Dergi (ISSN Eşleşmesi)
Chemistry and Biodiversity
Q3
SJR Skoru0,425
H-Index87
YayıncıWiley-Blackwell
ÜlkeUnited States
Biochemistry (Q3)
Bioengineering (Q3)
Chemistry (miscellaneous) (Q3)
Medicine (miscellaneous) (Q3)
Molecular Biology (Q4)
Molecular Medicine (Q4)
Metrikler
6
Atıf
13
Yazar
4
Anahtar Kelime