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Glutamate, Humic Acids and Their Combination Modulate the Phenolic Profile, Antioxidant Traits, and Enzyme-Inhibition Properties in Lettuce

Plants · Mayıs 2023

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YÖKSİS Kayıtları
Glutamate, humic acids and their combination modulate the phenolic profile, antioxidant traits, and enzyme-ınhibition properties in lettuce
Plants · 2023 SCI-Expanded
ARAŞTIRMA GÖREVLİSİ FATMA NUR ALP TURGUT →
Glutamate, humic acids and their combination modulate the phenolic profile, antioxidant traits, and enzyme-ınhibition properties in lettuce
Plants · 2023 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
Glutamate, humic acids and their combination modulate the phenolic profile, antioxidant traits, and enzyme-ınhibition properties in lettuce
Plants · 2023 SCI-Expanded
DOÇENT BÜŞRA ARIKAN ABDULVELİ →

Makale Bilgileri

DergiPlants
Yayın TarihiMayıs 2023
Cilt / Sayfa12
Erişim🔓 Açık Erişim
Özet Lettuce (Lactuca sativa L., Asteraceae) is a popular vegetable leafy crop playing a relevant role in human nutrition. Nowadays, novel strategies are required to sustainably support plant growth and elicit the biosynthesis of bioactive molecules with functional roles in crops including lettuce. In this work, the polyphenolic profile of lettuce treated with glutamic acid (GA), humic acid (HA), and their combination (GA + HA) was investigated using an untargeted metabolomics phenolic profiling approach based on high-resolution mass spectrometry. Both aerial and root organ parts were considered, and a broad and diverse phenolic profile could be highlighted. The phenolic profile included flavonoids (anthocyanins, flavones, flavanols, and flavonols), phenolic acids (both hydroxycinnamics and hydroxybenzoics), low molecular weight phenolics (tyrosol equivalents), lignans and stilbenes. Overall, GA and HA treatments significantly modulated the biosynthesis of flavanols, lignans, low molecular weight phenolics, phenolic acids, and stilbene. Thereafter, antioxidant capacity was evaluated in vitro with 2,2-diphenyln-1-picrylhydrazyl (DPPH), 2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), ferric reducing antioxidant power (FRAP), and cupric ion reducing antioxidant capacity (CUPRAC) assays. In addition, this study examined the inhibitory properties of enzymes, including acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), tyrosinase, alpha-amylase, and alpha-glucosidase. Compared to individual treatments, the combination of GA + HA showed stronger antioxidant abilities in free radical scavenging and reducing power assays in root samples. Moreover, this combination positively influenced the inhibitory effects of root samples on AChE and BChE and the tyrosinase inhibitory effect of leaf samples. Concerning Pearson’s correlations, antioxidant and enzyme inhibition activities were related to phenolic compounds, and lignans in particular correlated with radical scavenging activities. Overall, the tested elicitors could offer promising insights for enhancing the functional properties of lettuce in agricultural treatments.

Yazarlar (9)

1
Marco Armando De Gregorio
ORCID: 0000-0003-2086-9048
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Fatma Nur Alp-Turgut
ORCID: 0000-0002-1884-2367
4
Fevzi Elbasan
5
Ceyda Ozfidan-Konakci
ORCID: 0000-0002-7134-0948
6
Busra Arikan
ORCID: 0000-0001-5313-0501
7
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
8
Leilei Zhang
ORCID: 0000-0002-9278-0459
9
Luigi Lucini
ORCID: 0000-0002-5133-9464

Anahtar Kelimeler

antioxidant enzyme inhibition functional applications lettuce metabolomics

Kurumlar

Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Università Cattolica del Sacro Cuore, Campus di Piacenza e Cremona
Piacenza Italy

Metrikler

2
Atıf
9
Yazar
5
Anahtar Kelime

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