Scopus
🔓 Açık Erişim
Unveiling the phytochemical and pharmacological potential of Mimusops maxima (Poiret) Vaughan-an endemic plant with potential therapeutic effects
Process Biochemistry · Eylül 2023
Makale Bilgileri
DergiProcess Biochemistry
Yayın TarihiEylül 2023
Cilt / Sayfa132 · 157-165
Scopus ID2-s2.0-85165659019
Erişim🔓 Açık Erişim
Özet
Mimusops maxima (Poiret) Vaughan is an endemic plant of Mauritius Island that has never been studied for neither its phytochemical nor pharmacological properties. Hence this study targeted to extract the phytochemicals using three different solvents and characterizion them through HPLC-MS-MS, alongside investigating their effects against chronic diseases. The methanolic extract beared the highest total phenolic and total flavonoid composition, (31.10 ± 0.25 gallic acid equivalents/gram (GAE/g) and 38.68 ± 0.34 rutin equivalent (mgRE/g)), respectively), succeeded by the ethyl acetate and aqueous extracts. The antioxidant assay demonstrated that the methanolic extract had the highest potency in terms of antioxidant potential. The most potent acetylcholinesterase enzyme inhibitor was the ethyl acetate extract (4.78 ± 0.28 mg GALAE/g) followed by the methanolic extract (4.48 ± 0.05 mgGALAE/g). The most inhibition of the tyrosinase enzyme was generated by the methanolic extract (122.53 ± 2.72 mg KAE/g),the ethyl acetate extract and aqueous extracts (113.96 ± 1.53 and 6.19 ± 0.30 mg KAE/g, respectively) followed and were behind the methanolic extract. The methanolic and ethyl acetate extracts can be formulated as tissanes and extracts as health supplements as a prophylaxis measure for non-communicable diseases pending further toxicological investigations.
Yazarlar (14)
1
Shanoo Suroowan
2
E. J. Llorent-Martínez
3
Sharida Fakurazi
ORCID: 0000-0001-8986-876X
4
Gokhan Zengin
ORCID: 0000-0001-6548-7823
5
Asaad Khalid
6
Izzaddinn E. Ahmed
7
Hafiz A. Makeen
8
Hassan A. Alhazmi
9
Mohammed Albratty
10
Syam Mohan
11
Asim Najmi
12
Bao Van
13
Hassan H. Abdallah
14
Mohamad Fawzi Mahomoodally
Anahtar Kelimeler
Cell analysis
Enzyme inhibitors
Natural products
Phenolics
Phyto-pharmaceutics
Kurumlar
Duy Tan University
Da Nang Viet Nam
Faculty of Medicine and Health Sciences
Serdang Malaysia
Jazan University
Jizan Saudi Arabia
National Center for Research Sudan
Khartoum Sudan
North-West University
Potchefstroom South Africa
Salahaddin University-Erbil
Erbil Iraq
Saveetha Dental College And Hospitals
Chennai India
Selçuk Üniversitesi
Selçuklu Turkey
Universidad de Jaén
Jaen Spain
Universiti Putra Malaysia
Serdang Malaysia
University of Mauritius
Reduit Mauritius
University of Petroleum and Energy Studies
Dehradun India
University of Tabuk
Tabuk Saudi Arabia
Metrikler
3
Atıf
14
Yazar
5
Anahtar Kelime