Scopus
YÖKSİS Eşleşti
A comparative study on chemical profiles and biological activities of different extracts of three Verbascum species from Turkey: In vitro, in silico and network pharmacological approaches
Biocatalysis and Agricultural Biotechnology · Eylül 2023
YÖKSİS Kayıtları
A comparative study on chemical profiles and biological activities of different extracts of three Verbascum species from Turkey: In vitro, in silico and network pharmacological approaches
Biocatalysis and Agricultural Biotechnology · 2023 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
Makale Bilgileri
DergiBiocatalysis and Agricultural Biotechnology
Yayın TarihiEylül 2023
Cilt / Sayfa52
Scopus ID2-s2.0-85169536673
Özet
The present study aimed to evaluate the antioxidant and enzyme inhibition properties of aerial part of Verbascum cheiranthifolium Boiss. V. myriocarpum Boiss. & Heldr. and V. pyroliforme (Boiss. & Heldr.) Kuntze as well as their chemical profiles. Results showed that MeOH and hydromethanol recovered the highest total polyphenolic content with highest content obtained from V. cheiranthifolium (27.61and 27.69 mg GAE/g respectively) and V. myriocarpum (24.24 and 25.34 GAE/g respectively). The estimated content of verbascoside was quite higher in V. cheiranthifolium (987.05–6780.07 mg/100 g) and V. myriocarpum (1506.47–6433.73 mg/100 g) than V. pyroliforme (49.54–121.97 mg/100 g). All extracts of V. cheiranthifolium (274.17–713.79 mg/100 g) and polar ones of V. myriocarpum (185.67–304.51 mg/100 g) accumulated higher chlorogenic acid content than V. pyroliforme extracts (36.33–112.56 mg/100 g). The latter species was dominated by luteolin-7-O-glucoside and apigenin-7-O-glucoside with highest content recorded from the hydromethanolic extract (639.70 and 196.14 mg/100 g respectively). Extracts of V. cheiranthifolium (46.15–48.74 mg TE/g) and V. myriocarpum (46.05–48.50 mg TE/g) exerted significantly higher scavenging activity than those from V. pyroliforme (12.77–34.64 mg TE/g). Highest significant anti-acetylcholinesterase activity was obtained by MeOH extract of V. pyroliforme (2.65 mg GALAE/g) and V. myriocarpum (2.57 mg GALAE/g). In conclusion, extracts from the three investigated Verbascum spp. can be a potential source of bioactive metabolites with interesting antioxidant and enzyme inhibition properties.
Yazarlar (10)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Sakina Yagi
3
Mirela Kopjar
ORCID: 0000-0001-6864-4652
4
Ina Ćorković
ORCID: 0000-0002-4478-5431
5
Abdullahi Ibrahim Uba
6
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
7
Sathish Kumar
8
Kannan RR Rengasamy
9
Yusra AlDhaheri
10
Ali H. Eid
Anahtar Kelimeler
Antioxidant
Chemical profile
Enzyme inhibition
Verbascum cheiranthifolium
V. myriocarpum and V. pyroliforme
Kurumlar
College of Medicine
Doha Qatar
İstanbul Arel Üniversitesi
Istanbul Turkey
Khartoum University
Khartoum Sudan
Saveetha Dental College And Hospitals
Chennai India
Selçuk Üniversitesi
Selçuklu Turkey
Sveučilište Josipa Jurja Strossmayera u Osijeku
Osijek Croatia
United Arab Emirates University
Al Ain United Arab Emirates
Metrikler
1
Atıf
10
Yazar
5
Anahtar Kelime