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Promising applications of phyto-fabricated silver nanoparticles: Recent trends in biomedicine

Biochemical and Biophysical Research Communications · Aralık 2023

Makale Bilgileri

DergiBiochemical and Biophysical Research Communications
Yayın TarihiAralık 2023
Cilt / Sayfa688
Özet The prospective contribution of phyto-nanotechnology to the synthesis of silver nanomaterials for biomedical purposes is attracting increasing interest across the world. Green synthesis of silver nanoparticles (Ag-NPs) through plants has been extensively examined recently, and it is now seen to be a green and efficient path for future exploitation and development of practical nano-factories. Fabrication of Ag-NPs is the process involves use of plant extracts/phyto-compounds (e.g.alkaloids, terpenoids, flavonoids, and phenolic compounds) to synthesise nanoparticles in more economical and feasible. Several findings concluded that in the field of medicine, Ag-NPs play a major role in pharmacotherapy (infection and cancer). Indeed, they exhibits novel properties but the reason is unclear (except some theoretical interpretation e.g. size, shape and morphology). But recent technological advancements help to address these questions by predicting the unique properties (composition and origin) by characterizing physical, chemical and biological properties. Due to increased list of publications and their application in the field of agriculture, industries and pharmaceuticals, issues relating to toxicity are unavoidable and question of debate. The present reviews aim to find out the role of plant extracts to synthesise Ag-NPs. It provides an overview of various phytocompounds and their role in the field of biomedicine (antibacterial, antioxidant, anticancer, anti-inflammatory etc.). In addition, this review also especially focused on various applications such as role in infection, oxidative stress, application in medical engineering, diagnosis and therapy, medical devices, orthopedics, wound healing and dressings. Additionally, the toxic effects of Ag-NPs in cell culture, tissue of different model organism, type of toxic reactions and regulation implemented to reduce associated risk are discussed critically. Addressing all above explanations, this review focus on the detailed properties of plant mediated Ag-NPs, its impact on biology, medicine and their commercial properties as well as toxicity.

Yazarlar (10)

1
Yugal Kishore Mohanta
2
Awdhesh Kumar Mishra
3
Jibanjyoti Panda
4
Ishani Chakrabartty
5
Bhaskar Sarma
ORCID: 0000-0002-8378-5805
6
Sujogya Kumar Panda
7
Hitesh Chopra
8
Gokhan Zengin
ORCID: 0000-0001-6548-7823
9
Mark G. Moloney
10
Majid Sharifi-Rad

Anahtar Kelimeler

Ag-NPs Biogenic reduction Biomedicine Biomolecules Phyto-fabrication Toxicity

Kurumlar

Chettinad Academy of Research and Education
Kelambakkam India
Dhemaji College
Dhemaji India
Indegene Pvt. Ltd.
Bengaluru India
Saveetha School of Engineering
Chennai India
Selçuk Üniversitesi
Selçuklu Turkey
University of Oxford
Oxford United Kingdom
University of Science and Technology
Techno City India
University of Zabol
Zabol Iran
Utkal University
Bhubaneswar India
Yeungnam University
Gyeongsan South Korea

Metrikler

7
Atıf
10
Yazar
6
Anahtar Kelime

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