Scopus
YÖKSİS Eşleşti
Exploring traditional and modern approaches for extracting bioactive compounds from Ferulago trachycarpa
Preparative Biochemistry and Biotechnology · Ocak 2024
YÖKSİS Kayıtları
Exploring traditional and modern approaches for extracting bioactive compounds from Ferulago trachycarpa
Preparative Biochemistry & Biotechnology · 2024 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
Makale Bilgileri
DergiPreparative Biochemistry and Biotechnology
Yayın TarihiOcak 2024
Scopus ID2-s2.0-85193399452
Özet
For more than two millennia, Ferulago species have been revered as therapeutic herbs, maintaining their significance in present-day folk medicine practices. Therefore, the present study was conducted to investigate the phytochemical composition, inhibitory effects on metabolic enzymes, and possible therapeutic applications of F. trachycarpa, specifically focusing on its efficacy in diabetes management, anticholinergic effects, and antioxidant capabilities. The current investigation comprised an evaluation of a range of extracts acquired via conventional and modern methodologies, such as soxhlet (SOX), maceration (MAC) accelerated solvent extraction (ASE), homogenizer-assisted extraction (HAE), supercritical fluid extraction (SFE), microwave-assisted extraction (MW), and ultrasound-assisted extraction (UAE). Various techniques were employed to assess their antioxidant capacity and enzyme inhibition. Furthermore, the research utilized ultra-high performance liquid chromatography-MS/MS (UHPLC-MS/MS) to ascertain the principal phenolic compounds that are responsible for the antioxidant capacity observed in the various F. trachycarpa extracts. Among these, extracts from HAE, ASE, and MW revealed the most promise across all methodologies tested for their antioxidant potential. Furthermore, SFE and MAC extracts inhibited the most enzymes, including cholinesterases, tyrosinase, α -amylase, and α -glycosidase, indicating their potential as efficient natural treatments for several health-related issues.
Yazarlar (10)
1
Shakel Ahmed
2
Nilofar
3
Aleksandra Cvetanović Kljakić
4
Alena Stupar
5
Biljana Lončar
6
Jelena Božunović
7
Uroš Gašić
8
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
9
Claudio Ferrante
10
Gokhan Zengin
ORCID: 0000-0001-6548-7823
Anahtar Kelimeler
Antioxidant
enzyme inhibition
Ferulago trachycarpa
supercritical fluid extraction
UHPLC-MS/MS
ultrasound
Kurumlar
CSIC-UAM - Instituto de Investigacion en Ciencias de la Alimentacion (CIAL)
Madrid Spain
Institute of Food Technology in Novi Sad
Novi Sad Serbia
Selçuk Üniversitesi
Selçuklu Turkey
University of Belgrade
Belgrade Serbia
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
University of Novi Sad
Novi Sad Serbia