Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Assessment of Serum Galectin-3 Levels in Patients with Gestational Diabetes Mellitus
Journal of Diabetology · Ocak 2023
YÖKSİS Kayıtları
Assessment of serum galectin-3 levels in patients with gestational diabetes mellitus
Medknow · 2023 ESCI
PROFESÖR SEDAT ABUŞOĞLU →
Assessment of serum galectin-3 levels in patients with gestational diabetes mellitus
Journal of Diabetology · 2023 Emerging Sources Citation Index
PROFESÖR ALİ ÜNLÜ →
Assessment of serum galectin-3 levels in patients with gestational diabetes mellitus
Journal of Diabetology · 2023 ESCI
DOKTOR ÖĞRETİM ÜYESİ MUSLU KAZIM KÖREZ →
Assessment of serum galectin-3 levels in patients with gestational diabetes mellitus
Medknow · 2023 ESCI
PROFESÖR ALİ ÜNLÜ →
Assessment of serum galectin-3 levels in patients with gestational diabetes mellitus
Journal of Diabetology · 2023 Emerging Sources Citation Index
PROFESÖR SÜLEYMAN BALDANE →
Makale Bilgileri
DergiJournal of Diabetology
Yayın TarihiOcak 2023
Cilt / Sayfa14 · 28-33
Scopus ID2-s2.0-85197665567
Erişim🔓 Açık Erişim
Özet
Objective: This study was aimed to compare serum galectin-3 (Gal-3) levels in gestational diabetes mellitus (GDM) and healthy pregnant women and to evaluate the relationship between insulin resistance parameters and serum Gal-3 levels. Materials and Methods: Fifty-nine pregnant women who were screened for GDM with oral glucose tolerance tests (OGTT) at the 24th-28th gestational weeks were included in the study. According to the results of OGTT, 34 pregnant women were included in the GDM group and 25 pregnant women were included in the control group. Results: Serum Gal-3 value was found to be similar in the GDM and control group (P < 0.471). However, there was a significant positive association between Gal-3 and fasting insulin (r = 0.509, P < 0.001) and homeostasis model assessment of insulin resistance (HOMA-IR) (r = 0.479, P < 0.001) in the whole pregnancies, and between Gal-3 levels and fasting insulin (r = 0.608, P < 0.001), HOMA-IR (r = 0.609, P < 0.001), and OGTT 60 min glucose (r = 0.444, P = 0.016) in the GDM patients. Conclusions: There was no difference in the last trimester serum Gal-3 levels between GDM and healthy pregnant women. However, a significant positive correlation was determined between Gal-3 and fasting insulin, HOMA-IR, and OGTT 60 min glucose values in the GDM group, and fasting insulin and HOMA-IR values in whole pregnancies. The results of our study support previous data reporting the relationship between Gal-3 and GDM through insulin resistance.
Yazarlar (8)
1
Süleyman Baldane
2
Murat Celik
3
M. K. Korez
ORCID: 0000-0001-9524-6115
4
Emine Gul Baldane
5
Sedat Abusoglu
ORCID: 0000-0002-2984-0527
6
Unlu Ali
7
Suleyman Hilmi Ipekci
ORCID: 0000-0003-4410-2212
8
Levent Kebapcilar
Anahtar Kelimeler
Galectin-3
gestational diabetes mellitus
subclinical inflammation
Kurumlar
Hisar Intercontinental Hospital
Istanbul Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
8
Yazar
3
Anahtar Kelime