Scopus
🔓 Açık Erişim
Exploring the chemical composition and biological effects of four Salvia hybrids: an innovative perspective on functional yields
eFood · Ekim 2024
Makale Bilgileri
DergieFood
Yayın TarihiEkim 2024
Cilt / Sayfa5
Scopus ID2-s2.0-85206152801
Erişim🔓 Açık Erişim
Özet
Genus Salvia is considered one of the largest genera of family Lamiaceae with many recorded species and hybrids of valuable biological importance. This study involved the phytochemical characterization of four Salvia hybrids (KNM23 (S. fructicosa × S. officinalis), KNM101 (S. aramiensis × S. officinalis), KNM5 (S. aramiensis × S. officinalis) and KNM12 (S. fructicosa × S. officinalis)) through measuring their total phenolic content (TPC) and total flavonoid content (TFC) together with profiling through UPLC/MSn analysis followed by investigation of their antioxidant activities and enzyme inhibitory potential through different techniques. Hybrid KNM23 presented significantly high concentration of both phenolic and flavonoid, displaying a TPC of 92.10 mg GAE/g and a TFC of 50.85 mg RE/g. The UPLC/MSn profiling resulted in the tentative identification of one hundred eighty components from different phytochemical classes mainly flavonoids, phenolic acids, phenyl propanoids, tannins and many others. The antioxidant assay showed that hybrid KNM23, a hybrid of S. fruticosa and S. officinalis, exhibited the highest antioxidant activity in the DPPH, ABTS, and PBD assays, measuring 436.38 mmol TE/g, 543.65 mmol TE/g, and 3.20 mmol TE/g, respectively. KNM23 and KNM12 showed no inhibition of AChE and α-glucosidase. However, KMN12 demonstrated highest BChE and tyrosinase 2.57 mg GALAE/g and 12.91 mg KAE/g, respectively. Our results suggest that the Salvia hybrids can be considered as natural sources of bioactive compounds in the development of health-promoting applications.
Yazarlar (10)
1
Nilofar
2
Nadire Pelin Bahadırlı
3
Esraa A. Elhawary
4
Omayma A. Eldahshan
ORCID: 0000-0002-0972-0560
5
Abdel Nasser B. Singab
6
Enver Saka
7
Carlos L. Cespedes-Acuña
ORCID: 0000-0002-3715-3268
8
Vasil Andruch
9
Alina Kalyniukova
10
Gokhan Zengin
ORCID: 0000-0001-6548-7823
Anahtar Kelimeler
enzyme inhibition
flavonoids
hybrids
Lamiaceae
quinones
Salvia
Kurumlar
Czech University of Life Sciences Prague
Prague Czech Republic
Faculty of Pharmacy - Ain Shams University
Cairo Egypt
Mustafa Kemal Üniversitesi
Antakya Turkey
Pavol Jozef Šafárik University in Košice
Kosice Slovakia
Selçuk Üniversitesi
Selçuklu Turkey
Universidad del Bio Bio
Concepcion Chile
University of G. d'Annunzio Chieti and Pescara
Chieti Italy