Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Echocardiographic and hemodynamic changes in patients with high-grade varicocele
Biomolecules and Biomedicine · Mayıs 2023
YÖKSİS Kayıtları
Echocardiographic and hemodynamic changes in patients with high-grade varicocele
Biomolecules and Biomedicine · 2023 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MUSLU KAZIM KÖREZ →
Makale Bilgileri
DergiBiomolecules and Biomedicine
Yayın TarihiMayıs 2023
Cilt / Sayfa23 · 510-516
Scopus ID2-s2.0-85160452491
Erişim🔓 Açık Erişim
Özet
Varicocele is abnormal tortuosity and dilatation of the pampiniform plexus veins within the spermatic cord. Varicocele is associated with testicular atrophy, hypogonadism, impaired semen analysis values, or decreased testosterone production. Varicocele is a progressive disease and should be treated because it may be a systemic disease that can be associated with cardiovascular abnormalities. We hypothesize in this study that cardiovascular and hemodynamic pathologies may occur in varicocele patients. In this prospective, multicentric, multidisciplinary study, patients diagnosed with high-grade left varicocele in the urology clinic underwent semen analysis, total testosterone determination, and scrotal Doppler ultrasonography. In addition, blood pressure measurement and echocardiographic evaluation were performed by blinded cardiologists in both the varicocele patients and the healthy control group. The study was carried out with 103 varicocele patients and 133 healthy individuals who formed the control group. Diastolic blood pressure (P= 0.016), left ventricular end diastolic (P < 0.001) and systolic diameter (P < 0.001), ejection fraction (P < 0.001), pulmonary arterial pressure (P < 0.001), and aortic distensibility (P < 0.001) values were significantly higher in varicocele patients compared with controls; interventricular septum wall thickness (P = 0.022), aortic systolic (P < 0.001) and diastolic diameter (P < 0.001), aortic systolic (P < 0.001) and diastolic diameter index (P < 0.001), and aortic stiffness index (P < 0.001) values were significantly lower in varicocele patients. The mean aortic distensibility of non-normozoospermic group was lower than that of normozoospermic group (P = 0.041). There was no statistically significant relationship between thickest vein diameter in spermatic cord and cardiological parameters. This study showed that symptomatic patients with high-grade varicocele had a higher risk of cardiovascular and hemodynamic disease. We recommend that men with high-grade symptomatic varicocele with impaired semen analysis undergo cardiovascular and hemodynamic evaluation regardless of their spermatic vein diameter.
Yazarlar (5)
1
Batuhan Ergani
ORCID: 0000-0002-4667-855X
2
Azmi Eyiol
ORCID: 0000-0003-2740-1966
3
Mustafa Karabiçak
ORCID: 0000-0001-7434-3899
4
Mesut Gitmez
ORCID: 0000-0003-1078-9095
5
M. K. Korez
ORCID: 0000-0001-9524-6115
Anahtar Kelimeler
Echocardiography
High grade varicocele
Semen analysis
Spermatic vein diameter
Kurumlar
Batman Regional State Hospital
Batman Turkey
Beyhekim Training and Research Hospital
Konya Turkey
Selçuk Tip Fakültesi
Konya Turkey