Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization
Journal of Enzyme Inhibition and Medicinal Chemistry · Aralık 2013
YÖKSİS Kayıtları
Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY · 2013 SCI
DOÇENT HANİF ŞİRİNZADE →
Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY · 2013 SCI
DOÇENT HANİF ŞİRİNZADE →
Makale Bilgileri
DergiJournal of Enzyme Inhibition and Medicinal Chemistry
Yayın TarihiAralık 2013
Cilt / Sayfa28 · 1143-1155
Scopus ID2-s2.0-84887458873
Erişim🔓 Açık Erişim
Özet
Melatonin (MLT) is a strong free-radical scavenger, which protects the body from the effects of oxidants. In recent years, MLT have been described resulting in much attention in the development of synthetic compounds possessing. As a part of our ongoing study a series of indole-based MLT analogue hydrazide/hydrazone derivatives were synthesized, characterized and in vitro antioxidant activity was investigated by evaluating their reducing effect against oxidation of a redox sensitive fluorescent probe. Membrane stabilizing effect of all compounds was also investigated by lactate dehydrogenase leakage assay. Furthermore voltammetric methods have been applied to the synthesized compounds to characterize oxidation potentials to get insight into their metabolism owing to the oxidation mechanisms taking place at the electrode and in the body share similar principles. © 2013 Informa UK, Ltd.
Yazarlar (7)
1
Sibel Süzen
2
Betul Tekiner-Gulbas
3
Hanif Şirinzade
4
Duysal Uslu
5
Hande Gurer-Orhan
6
Mehmet Gumustas
7
Sibel A. Özkan
Anahtar Kelimeler
Antioxidant activity
Hydrazone/hydrazide
Indole
Melatonin
Synthesis
Voltammetry
Kurumlar
Ankara Üniversitesi
Ankara Turkey
Ege Üniversitesi
Izmir Turkey
Metrikler
32
Atıf
7
Yazar
6
Anahtar Kelime