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Insufficiency of positive airway pressure treatment on increased mean platelet volume: a prospective controlled study in patients with obstructive sleep apnea syndrome

Sleep and Breathing · Eylül 2020

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YÖKSİS Kayıtları
Insufficiency of positive airway pressure treatment on increased mean platelet volume: a prospective controlled study in patients with obstructive sleep apnea syndrome
Sleep and Breathing · 2019 SCI-Expanded
PROFESÖR BÜLENT ULUSOY →

Makale Bilgileri

DergiSleep and Breathing
Yayın TarihiEylül 2020
Cilt / Sayfa24 · 885-891
Özet Background: To analyze the association between obstructive sleep apnea syndrome (OSAS) and some hematological variables such as mean platelet volume (MPV), platelet distribution width (PDW), and the impact of positive airway pressure (PAP) treatment on these parameters. Methods: The participants of the present prospective study consist of 36 OSAS patients diagnosed with polysomnography and recommended PAP treatment and 30 healthy members as the control group. Complete blood analyses were conducted to the patient group twice; before the initiation of the PAP treatment and 1 month after regular PAP use. The control group was administered a complete blood analyses only once. Patient and control group were compared in terms of various parameters such as MPV, PDW, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), white blood cell (WBC) values, and platelet counts. Results: MPV value of the patient group was before and after PAP treatment significantly higher than the control group (respectively; Z = 2.246; p = 0.025, and Z = 2.033; p = 0.042). However, there were no statistically significant differences in the values before and after PAP treatment in the patient group (Z = 0.727; p = 0.467). In terms of platelet numbers and PDW values, no significant differences were determined (p > 0.05). Conclusion: MPV value was significantly elevated in OSAS patients. However, the 1 month of PAP treatment was insufficient in decreasing elevated MPV values.

Yazarlar (6)

1
Bülent Ulusoy
ORCID: 0000-0001-7643-7100
2
Tolga Oğuzhan
3
Mesut Akyol
4
K. Bozdemir
5
Bülent Çiftçi
6
H. Korkmaz

Anahtar Kelimeler

Continuous positive airway pressure Mean platelet volume Obstructive sleep apnea syndrome Thrombosis

Kurumlar

Ankara Yildirim Beyazit University
Ankara Turkey
Bozok Üniversitesi
Yozgat Turkey
Medical Park Hospital
Bursa Turkey
Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

2
Atıf
6
Yazar
4
Anahtar Kelime

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