Scopus
Clinical characteristics and outcomes of COVID-19 in patients with type 2 diabetes in Turkey: A nationwide study (TurCoviDia)
Journal of Diabetes · Temmuz 2021
Makale Bilgileri
DergiJournal of Diabetes
Yayın TarihiTemmuz 2021
Cilt / Sayfa13 · 585-595
Scopus ID2-s2.0-85102931455
Özet
Background: Coronavirus disease 2019 (COVID-19) has been reported to be associated with a more severe course in patients with type 2 diabetes mellitus (T2DM). However, severe adverse outcomes are not recorded in all patients. In this study, we assessed disease outcomes in patients with and without T2DM hospitalized for COVID-19. Methods: A nationwide retrospective cohort of patients with T2DM hospitalized with confirmed COVID-19 infection from 11 March to 30 May 2020 in the Turkish Ministry of Health database was investigated. Multivariate modeling was used to assess the independent predictors of demographic and clinical characteristics with mortality, length of hospital stay, and intensive care unit (ICU) admission and/or mechanical ventilation. Results: A total of 18 426 inpatients (median age [interquartile range, IQR]: 61 [17] years; males: 43.3%) were investigated. Patients with T2DM (n = 9213) were compared with a group without diabetes (n = 9213) that were matched using the propensity scores for age and gender. Compared with the group without T2DM, 30-day mortality following hospitalization was higher in patients with T2DM (13.6% vs 8.7%; hazard ratio 1.75; 95% CI, 1.58-1.93; P <.001). The independent associates of mortality were older age, male gender, obesity, insulin treatment, low lymphocyte count, and pulmonary involvement on admission. Older age, low lymphocyte values, and pulmonary involvement at baseline were independently associated with longer hospital stay and/or ICU admission. Conclusions: The current study from the Turkish national health care database showed that patients with T2DM hospitalized for COVID-19 are at increased risk of mortality, longer hospital stay, and ICU admission.
Yazarlar (18)
1
Alper Sonmez
2
Ibrahim Demirci
ORCID: 0000-0002-6808-8550
3
Cem Haymana
4
İlker Taşçı
5
Selçuk Daǧdelen
6
Serpil Salman
7
Naim Ata
8
Ibrahim Sahin
9
Rıfat Emral
10
Erman Çakal
ORCID: 0000-0003-4455-7276
11
Aysegul Atmaca
12
Mustafa Sahin
ORCID: 0000-0002-4718-0083
13
Osman Celik
14
Tevfik Demir
ORCID: 0000-0003-0319-9572
15
Derun Ertugrul
16
Ugur Unluturk
17
Murat Caglayan
18
Ilhan Satman
Anahtar Kelimeler
COVID-19
hospital stay
intensive care unit admission
mortality
type 2 diabetes
Kurumlar
Ankara Provincial Health Directorate
Ankara Turkey
Ankara Üniversitesi
Ankara Turkey
Dokuz Eylül Üniversitesi
Izmir Turkey
Hacettepe Üniversitesi
Ankara Turkey
Inönü Üniversitesi
Malatya Turkey
İstanbul Tıp Fakültesi
Istanbul Turkey
Medica Clinic
Istanbul Turkey
Ondokuz Mayis Üniversitesi
Samsun Turkey
T.C. Sağlık Bakanlığı,
Ankara Turkey
Turkish Institute of Public Health and Chronic Diseases
Istanbul Turkey
University of Health Sciences
Istanbul Turkey
Metrikler
29
Atıf
18
Yazar
5
Anahtar Kelime