Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Design of an electrochemical biosensing system for xanthine detection and a study on binding interaction of ketoconazole with xanthine oxidase
Colloids and Surfaces A Physicochemical and Engineering Aspects · Mart 2014
YÖKSİS Kayıtları
Design of an electrochemical biosensing system for xanthine detection and a study on binding interaction of ketoconazole with xanthine oxidase
Colloids and Surfaces A: Physicochemical and Engineering Aspects · 2014 SCI-Expanded 1 atıf
Prof. Dr. SALİH ZEKİ BAŞ →
Design of an electrochemical biosensing system for xanthine detection and a study on binding interaction of ketoconazole with xanthine oxidase
Colloids and Surfaces A: Physicochemical and Engineering Aspects · 2014 SCI-Expanded
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Recovery and concentration of metals from red mud by Donnan dialysis
2003 ISSN: 09277757 SCI-Expanded
Prof. Dr. SAİT GEZGİN →
Interaction of donepezil with human serum albumin on amine modified magnetic nanoparticles
2014 ISSN: 0927-7757 SCI 4 atıf
Prof. Dr. MUSTAFA ÖZMEN →
Design of an electrochemical biosensing system for xanthine detection and a study on binding interaction of ketoconazole with xanthine oxidase
2014 ISSN: 09277757 SCI-Expanded
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Interaction of donepezil with human serum albumin on amine modified magnetic nanoparticles
2014 ISSN: 09277757 SCI-Expanded 1 atıf
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Design of an electrochemical biosensing system for xanthine detection and a study on binding interaction of ketoconazole with xanthine oxidase
2014 ISSN: 09277757 SCI-Expanded 1 atıf
Prof. Dr. SALİH ZEKİ BAŞ →
Chemical modification kinetics of polystyrenes having various molecular weights
2007 ISSN: 09277757 SCI-Expanded 1 atıf
Prof. Dr. SALİH ZEKİ BAŞ →
Electrochemical determination of Cu II ions using glassy carbon electrode modified by some nanomaterials and 3 nitroaniline
2015 ISSN: 09277757 SCI-Expanded
Prof. Dr. MUSTAFA ERSÖZ →
Electrochemical stability and repulsion of polypyrrole film
2013 ISSN: 09277757 SCI-Expanded
Prof. Dr. YASEMİN ÖZTEKİN →
Electrochemical determination of Cu II ions using glassy carbon electrode modified by some nanomaterials and 3 nitroaniline
2015 ISSN: 09277757 SCI-Expanded
Prof. Dr. YASEMİN ÖZTEKİN →
Electrochemical determination of Cu II ions using glassy carbon electrode modified by some nanomaterials and 3 nitroaniline
2015 ISSN: 09277757 SCI-Expanded
Prof. Dr. ZAFER YAZICIGİL →
Recovery and concentration of metals from red mud by Donnan dialysis
2003 ISSN: 09277757 SCI-Expanded
Prof. Dr. SAİT GEZGİN →
Investigating sorption characteristics of copper ions onto insolubilized humic acid by using a continuously monitored solid phase extraction technique
2007 ISSN: 0927-7757 SCI-Expanded
Prof. Dr. HÜSEYİN KARA →
Use of aminoprophyl silica immobilized humic acid for Cu II ions removal from aqueous solution by using a continuously monitored solid phase extraction technique in a column arrangement
2008 ISSN: 09277757 SSCI
Prof. Dr. HÜSEYİN KARA →
Haloalkanes and aromatic hydrocarbons sensing using Langmuir-Blodgett thin film of pillar[5]arene-biphenylcarboxylic acid
2019 ISSN: 0927-7757 SCI-Expanded
Prof. Dr. AHMED NURİ KURŞUNLU →
Investigating sorption characteristics of copper ions onto insolubilized humic acid by using a continuously monitored solid phase extraction technique
2007 ISSN: 09277757 SCI-Expanded 12 atıf
Prof. Dr. HAMİDE FİLİZ AYYILDIZ →
Use of aminoprophyl silica immobilized humic acid for Cu II ions removal from aqueous solution by using a continuously monitored solid phase extraction technique in a column arrangement
2008 ISSN: 09277757 SCI-Expanded 13 atıf
Prof. Dr. HAMİDE FİLİZ AYYILDIZ →
Calixarene-tethered textile fabric for the efficient removal of hexavalent chromium from polluted water
2021 ISSN: 0927-7757 SCI-Expanded Q2
Prof. Dr. SERKAN ERDEMİR →
Preparation of poly(ε-caprolactone) nanofibrous mats incorporating graphene oxide-silver nanoparticle hybrid composite by electrospinning method for potential antibacterial applications
2022 ISSN: 0927-7757 SCI-Expanded Q2
Dr. Öğr. Üyesi FATİH SEVGİ →
Makale Bilgileri
ISSN09277757
Yayın TarihiMart 2014
Cilt / Sayfa444 · 40-47
Scopus ID2-s2.0-84891951115
Özet
Xanthine oxidase (XO) was successfully immobilized by covalent attachment on poly(glycidyl methacrylate-co-vinylferrocene) (P(GMA-co-VFc)), a redox copolymer containing pendant epoxy and ferrocene moieties, for the evaluation of both the biosensing properties and the effect of the interaction of ketoconazole (Ktc) with the immobilized XO. The binding interaction between Ktc, a drug used to treat fungal infections, and the immobilized XO on P(GMA-co-VFc) was also studied by fluorescence spectroscopy technique. The binding capacity of the drug was determined using a calibration curve equation that was drawn at excitation wavelength of 300nm using fluorescence spectroscopy. The interaction ability was confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and native-PAGE analysis. The enzyme electrode exhibited a linear range from 2.7×10-3 to 0.55mM with a sensitivity of 19.42μAmM-1cm-2 and a detection limit of 8×10-4mM for the detection of xanthine. The activation energy (Ea) and the apparent Michaelis-Menten constant (Kmapp) values were found to be 12.30kJmol-1 and 0.38mM, respectively. © 2013 Elsevier B.V.
Yazarlar (4)
1
Salih Zeki Bas
ORCID: 0000-0003-2822-8851
2
Esra Maltas Cagil
3
Busra Sennik
4
Faruk Yilmaz
Anahtar Kelimeler
Biosensor
Fluorescence
Ketoconazole
Protein-drug interaction
Xanthine oxidase
Kurumlar
Gebze Teknik Üniversitesi
Gebze Turkey
Istanbul Medeniyet University
Istanbul Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Colloids and Surfaces A: Physicochemical and Engineering Aspects
Q1
SJR Skoru0,866
H-Index213
YayıncıElsevier B.V.
ÜlkeNetherlands
Physical and Theoretical Chemistry (Q1)
Colloid and Surface Chemistry (Q2)
Surfaces and Interfaces (Q2)
Metrikler
19
Atıf
4
Yazar
5
Anahtar Kelime