Scopus
YÖKSİS Eşleşti
Evaluation of Postmortem Cerebrospinal Fluid S100B Protein and Serotonin Levels: Comparison of Suicidal Versus Nonsuicidal Deaths in Konya, Turkey
Journal of Forensic Sciences · Eylül 2016
YÖKSİS Kayıtları
Evaluation of Postmortem Cerebrospinal Fluid S100B Protein and Serotonin Levels Comparison of Suicidal Versus Nonsuicidal Deaths in Konya Turkey
JOURNAL OF FORENSIC SCIENCES · 2016 SCI
PROFESÖR KAMİL HAKAN DOĞAN →
Makale Bilgileri
DergiJournal of Forensic Sciences
Yayın TarihiEylül 2016
Cilt / Sayfa61 · 1285-1291
Scopus ID2-s2.0-85027917203
Özet
Although suicide is a preventable public health problem, objective assays for suicide risk are limited. In this study, it was aimed to determine levels of S100B protein and serotonin as a marker for risk of suicide. S100B protein and serotonin levels were investigated with ELISA method in the cerebrospinal fluid (CSF) in medicolegal autopsy cases, including those of suicide cases (n = 32) and nonsuicide cases (n = 56). The CSF S100B levels were higher (9.3 ± 2.9 ng/mL vs. 5.4 ± 2.0 ng/mL), and serotonin levels were lower (10.4 ± 4.9 ng/mL vs. 19.0 ± 5.7 ng/mL) in suicide group than nonsuicide group (p < 0.05). There was no correlation between S100B protein and serotonin levels with gender, age groups, postmortem interval, and cause of death. It is concluded that both S100B protein and serotonin in CSF may be useful for determination of suicide risk.
Yazarlar (3)
1
Kamil Hakan Dogan
ORCID: 0000-0002-7685-266X
2
Mustafa Unaldi
3
Serafettin Demirci
Anahtar Kelimeler
death
forensic science
postmortem
S100B
serotonin
suicide
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Private Ticaret Borsasi Hospital
Konya Turkey
Selçuk Tip Fakültesi
Konya Turkey
Metrikler
11
Atıf
3
Yazar
6
Anahtar Kelime