Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Comparison of two different radiotherapy techniques in stomach cancer paiients who underwent concomitant chemoradiotherapy
Medical Journal of Bakirkoy · Ocak 2014
YÖKSİS Kayıtları
Mide kanseri nedeni ile eş zamanlı kemoradyoterapi uygulanan hastalarda iki farklı radyoterapi tekniğinin karşılaştırılması
BAKIRKÖY TIP DERGİSİ · 2013 TR DİZİN
DOÇENT OSMAN VEFA GÜL →
Makale Bilgileri
DergiMedical Journal of Bakirkoy
Yayın TarihiOcak 2014
Cilt / Sayfa10 · 11-17
Scopus ID2-s2.0-84896993444
Erişim🔓 Açık Erişim
Özet
Objective: We aimed to compare four field radiotherapy techniques with three field radiotherapy technique with enhanced dynamic wedges (EDW) in patients with stomach cancer who underwent postoperative chemo-radiotherapy. Material and Methods: Ten consecutive stomach cancer patients who underwent total/subtotal gastrectomy and lymph node dissection were included to the study. For each patient, two different treatment plans were created for the tumor bed and regional lymph nodes. Three field and four field plans were compared for the doses in the planning target volume (PTV), the organ at risk (OAR) volumes (including kidneys, liver, spleen and spinal cord), the dose homogeneity index (DHI), and the monitor unit counts (MU) required for the treatment. Student-t test was used for statistical analysis. Results: There was no difference between two techniques in terms of DHI (p:0.576). The mean dose received by the liver was significantly reduced with three field technique (p<0.001); whereas the mean doses of the kidneys, spleen and spinal cord were decreased with four field technique (p values were 0.007, 0.021 and <0.001 respectively). The dose to %10, %30, %40 and %50 of the total liver volume were significantly reduced with three field technique (p values were 0.026, 0.009, 0.001 and <0.001 respectively). The MU counts required for the treatment was significantly lower with four filed technique (p<0.001). Conclusion: There weren't any difference in terms of dose homogeneity in the PTV and DHI between four field technique and three field techniques with EDW in patients with stomach cancer who underwent radiotherapy to the tumor bed and regional lymph nodes. It was expected to need more MU in the three field technique with EDW. The liver dose was significantly reduced with three field technique. Therefore it is more convenient to choose three field techniques with EDW in patients with known liver disease.
Yazarlar (6)
1
Güler Yavaş
2
Çaǧdaş Yavaş
3
Gökçen Çobanoǧlu
4
Osman Vefa Gul
ORCID: 0000-0002-6773-3132
5
Hilal Acar
6
Özlem Ata
Anahtar Kelimeler
Dose volume histograms
Radiotherapy
Stomach cancer
Kurumlar
İstanbul Medipol Üniversitesi
Istanbul Turkey
Konya Eǧitim Araştirma Hastanesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey