Scopus
YÖKSİS Eşleşti
Dosimetric Comparison of Three-Dimensional Conformal Radiotherapy, Dynamic Intensity Modulated Radiation Therapy, and Hybrid Planning for Treatment of Locally Advanced Lung Cancer
Middle East Journal of Cancer · Temmuz 2022
YÖKSİS Kayıtları
Dosimetric Comparison of Three-Dimensional Conformal Radiotherapy, Dynamic Intensity Modulated Radiation Therapy, and Hybrid Planning for Treatment of Locally Advanced Lung Cancer
Middle East Journal of Cancer · 2021 Emerging Sources Citation Index
DOÇENT HAMİT BAŞARAN →
Dosimetric Comparison of Three-Dimensional ConformalRadiotherapy, Dynamic Intensity Modulated Radiation Therapy, and Hybrid Planning for Treatment of Locally Advanced Lung Cancer
Middle East Journal of Cancer · 2022 ESCI
DOÇENT OSMAN VEFA GÜL →
Dosimetric Comparison of Three-Dimensional Conformal Radiotherapy, Dynamic Intensity Modulated Radiation Therapy, and Hybrid Planning for Treatment of Locally Advanced Lung Cancer
Middle East Journal of Cancer · 2021 Emerging Sources Citation Index
DOKTOR ÖĞRETİM ÜYESİ MÜRSEL DÜZOVA →
Makale Bilgileri
DergiMiddle East Journal of Cancer
Yayın TarihiTemmuz 2022
Cilt / Sayfa13 · 523-530
Scopus ID2-s2.0-85134374075
Özet
Background: The present dosimetric study aimed to evaluate the dosimetric benefits of using three-dimensional conformal radiotherapy (3D-CRT), dynamic intensity-modulated radiation therapy (D-IMRT), and Hybrid CRT/IMRT plans. Method: In this dosimetric research, 10 patients with locally advanced lung cancer (Stage-IIIB) were selected. The patients with centrally located tumors were particularly chosen to underline the complexity of the treatment plans. We performed 3D-CRT, D-IMRT, and Hybrid CRT/IMRT treatment plans using Varian with the Eclipse treatment planning system. The treatment plans were compared with respect to the doses received by the organs at risk, including total lungs, contralateral lung, ipsilateral lung, heart, spinal cord, esophagus, the dose homogeneity index, and conformity indexes. Paired samples t-test was performed for statistical analyses. Results: Hybrid method significantly advanced the target conformity index when compared with 3D-CRT and D-IMRT methods (P = 0.000). The total lung volume receiving 5 to 10 Gy was significantly lower in the 3D-CRT plans compared with that in D-IMRT and Hybrid plans (P = 0.025 and P = 0.003). V20 of the total lung was significantly lower in Hybrid plans (P =0.036). The average mean doses to heart in all the plans were similar with no significant differences. There was a statistically significant difference concerning the maximum doses for spinal cord, when D-IMRT plans were compared with 3D-CRT and Hybrid (P = 0.000). Conclusion: Hybrid technique could be highly conducive to the treatment, while 3D-CRT and D-IMRT techniques are not adequate alone for maintaining the spinal cord, heart, and esophagus in the treatment of LALC patients.
Yazarlar (4)
1
Hamit Basaran
2
Gokcen Inan
ORCID: 0000-0003-2995-0256
3
Osman Vefa Gul
ORCID: 0000-0002-6773-3132
4
Mursel Duzova
Anahtar Kelimeler
Intensity-modulated radiotherapy
Lung neoplasms
Three-dimensional conformal radiotherapy
Kurumlar
Selçuk Tip Fakültesi
Konya Turkey
Metrikler
1
Atıf
4
Yazar
3
Anahtar Kelime