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Scopus YÖKSİS DOI Eşleşti SJR Q2

Protective effect of melatonin against radiobiological damage in the brain of rats exposed to low and high dose rate radiotherapy

Radiation Physics and Chemistry · Kasım 2024

YÖKSİS DOI Eşleşmesi Bulundu

Bu Scopus makalesi YÖKSİS veritabanında da kayıtlı. Aşağıda YÖKSİS verilerini görebilirsiniz.

YÖKSİS Kayıtları
Protective effect of melatonin against radiobiological damage in the brain of rats exposed to low and high dose rate radiotherapy
Radiation Physics and Chemistry · 2024 SCI-Expanded
Prof. Dr. FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Protective effect of melatonin against radiobiological damage in the brain of rats exposed to low and high dose rate radiotherapy
Radiation Physics and Chemistry · 2024 SCI-Expanded
Prof. Dr. HALUK ÖZPARLAK →
Protective effect of melatonin against radiobiological damage in the brain of rats exposed to low and high dose rate radiotherapy
Radiation Physics and Chemistry · 2024 SSCI
Doç. Dr. KURTULUŞ PARLAK →
Protective effect of melatonin against radiobiological damage in the brain of rats exposed to low and high dose rate radiotherapy
Radiation Physics and Chemistry · 2024 SCI-Expanded
Doç. Dr. OSMAN VEFA GÜL →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
EPR investigation of gamma irradiated single crystal guaifenesin A combined experimental and computational study
2016 ISSN: 0969806X SCI
Prof. Dr. ÜLKÜ AKPINAR →
Magnetic properties of single crystal alpha benzoin oxime An EPR study
2012 ISSN: 0969806X SCI
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Magnetic properties of gamma irradiated single crystals of cholesteryl chloride An EPR study
2011 ISSN: 0969806X SCI
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EPR study of gamma irradiated 2 5 di tert butyl hydroquinone single crystals
2011 ISSN: 0969806X SCI
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CW EPR study of 2 2 4 4 tetramethyl 3 pentanone oxime single crystals
2010 ISSN: 0969806X SCI
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EPR study of gamma irradiated single crystal 4 phenylsemicarbazide
2010 ISSN: 0969806X SCI
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Determination of the irradiation effects on senna (Casia acutifolia) leaves by ESR technique and microbiological analysis
2019 ISSN: 0969-806X SCI-Expanded Q1
Dr. Öğr. Üyesi MAHMUT ÖZGÜR SEZER →
Gamma irradiation effects on EuBa2Cu3O7 high temperature superconductor
2013 ISSN: 0969-806X SCI-Expanded
Prof. Dr. NURCAN AKDURAN →
The dosimetric comparison and evaluation of helical tomotherapy, volumetric-modulated arc radiotherapy (VMAT), step-and-shoot and sliding window radiotherapy techniques in nasopharyngeal carcinoma
2022 ISSN: 0969-806X SCI-Expanded Q1
Prof. Dr. NİHAL BÜYÜKÇİZMECİ →
Dosimetric evaluation of three-phase adaptive radiation therapy in head and neck cancer
2023 ISSN: 0969-806X SCI-Expanded Q1
Doç. Dr. HAMİT BAŞARAN →
Dosimetric evaluation of three-phase adaptive radiation therapy in head and neck cancer
2023 ISSN: 0969-806X SCI-Expanded Q1
Doç. Dr. HAMİT BAŞARAN →
Paramagnetic characterization and dosimetric properties of Airfix drug and its ingredients (Montelukast sodium, Sorbitol): An EPR and DFT study
2022 ISSN: 0969-806X SCI Q1
Prof. Dr. ÜLKÜ AKPINAR →
Experimental evaluation of out-of-field dose for different high-energy electron beams and applicators used in external beam radiotherapy
2024 ISSN: 0969-806X SCI-Expanded Q1
Doç. Dr. OSMAN VEFA GÜL →
Effect of different CTV shrinkage and skin flash margins on skin dose for left chest wall IMRT: A dosimetric study
2024 ISSN: 0969-806X SCI-Expanded Q1
Doç. Dr. OSMAN VEFA GÜL →
The effect of radiation on grape seeds: ESR and microbiological analysis
2023 ISSN: 0969-806X SCI-Expanded Q1
Dr. Öğr. Üyesi MAHMUT ÖZGÜR SEZER →
The effect of radiation on grape seeds: ESR and microbiological analysis
2023 ISSN: 0969-806X SCI-Expanded Q2
Dr. Öğr. Üyesi MAHMUT ÖZGÜR SEZER →
The effect of radiation on grape seeds: ESR and microbiological analysis
2023 ISSN: 0969-806X SCI-Expanded Q1
Prof. Dr. ÜLKÜ AKPINAR →
Synergizing electrical, mechanical, and radiation shielding properties of dendritic copper filled epoxy polymer composites
2024 ISSN: 0969-806X SCI-Expanded Q1
Doç. Dr. HARUN SEPETÇİOĞLU →
Investigation of the effect of bolus on skin dose in breast cancer treatment with tomotherapy and LINAC radiotherapy devices
2024 ISSN: 0969-806X SCI-Expanded Q1
Doç. Dr. OSMAN VEFA GÜL →
Examining the effect of bolus use on skin dose during postmastectomy radiotherapy using in vivo thermoluminescence dosimetry: An IMRT and a 3DCRT study
2024 ISSN: 0969-806X SCI-Expanded Q1
Doç. Dr. OSMAN VEFA GÜL →

Makale Bilgileri

Dergi Radiation Physics and Chemistry
ISSN0969806X
Yayın TarihiKasım 2024
Cilt / Sayfa224
DOI10.1016/j.radphyschem.2024.112098
Scopus ID2-s2.0-85199926089
Özet This study aimed to investigate the radioprotective effect of melatonin (MLT) on brain damage in rats exposed to low and high dose rate radiotherapy. The dose rates of 10 MV photon beams used in the study were 600 MU/min and 2400 MU/min for low dose rate radiotherapy (LDR_RT) and high dose rate radiotherapy (HDR_RT), respectively. A total of 46 female Wistar albino rats aged between 8 and 12 weeks were divided in 6 groups. These groups were control, MLT, LDR_RT, HDR_RT, LDR_RT plus MLT and HDR_RT plus MLT, respectively. Rats in the radiation group received 16 Gy single dose whole body radiotherapy. Rats in the LDR_RT plus MLT and HDR_RT plus MLT groups received 10 mg/kg melatonin by intraperitoneal injection 15 min before radiotherapy. The rats were sacrificed 48 h after radiotherapy. Biochemical and histopathological methods analyzed radiation damage in rats. There was a statistically significant difference between the LDR_RT and HDR_RT radiation groups and the control group in terms of biochemical and histopathological parameters (p < 0.05). In the groups that received only LDR_RT and HDR_RT, the moderate neuro-degeneration scores were 1 and 4, respectively, while the moderate neuro-degeneration scores were 0 and 2 when MLT was applied to these groups. Superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) enzymes were decreased due to radiotherapy, whereas these enzymes were improved in MLT-treated groups. In conclusion, melatonin was found to be effective as a radioprotective agent in the prevention of brain damage caused by exposure to 10 MV photon radiation at dose rates of 600 MU/min and 2400 MU/min.

Yazarlar (7)

1
Osman Vefa Gul
ORCID: 0000-0002-6773-3132
2
Kurtuluş Parlak
ORCID: 0000-0002-8656-037X
3
Fatma Humeyra Yerlikaya Aydemir
4
Ibrahim Babalıoglu
5
Umit Ozdemir
6
Mehmet Koc
7
Haluk Ozparlak

Anahtar Kelimeler

Brain Dose rate effect Melatonin Radiotherapy

Kurumlar

Konya City Hospital
Konya Turkey
Konya Veterinary Control Institute
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Radiation Physics and Chemistry
Q2
SJR Skoru0,536
H-Index111
YayıncıElsevier Ltd
ÜlkeUnited Kingdom
Radiation (Q2)
Dergi sayfasına git

Metrikler

5
Atıf
7
Yazar
4
Anahtar Kelime

Sistemimizdeki Yazarlar

OG
OSMAN VEFA GÜL
Doç. Dr.

Hızlı Erişim

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