Background: The metacarpus, one of the forelimb bones, is an important bone used in zooarchaeological studies and estimating shoulder height in sheep. Morphometric measurements were performed using different methods on the metacarpus of different sheep breeds. Objectives: The study aims to measure the metacarpal bones morphometrically in different sheep breeds and model them with a 3D scanner. In addition, the compatibility of the two different methods was evaluated by comparing the measurements made with digital calipers and 3D models. Methods: In the study, metacarpal bones of eight adult, healthy male Akkaraman sheep and eight adult, healthy male Merino sheep were used. After the bones were macerated, 17 different morphometric measurements were performed with a digital caliper. Then, 3D models of the bones were obtained using a 3D scanner. The same morphometric measurements were made on the models using the scanner software. Results: According to the morphometric measurement results made with digital caliper, no statistical difference was observed in greatest length (GL) and antero-posterior diameter of external trochlea of condylus medialis (DEM) parameters in Akkaraman and Merino sheep. Differences were observed in all other parameters. In the measurements made on the model, no statistical difference was observed in the GL, DEM, and antero-posterior diameter of external trochlea of condylus lateralis (DEL) parameters. Differences were observed in all other parameters. In both methods, it was observed that the values belonging to the Merino sheep were higher in the parameters where statistical differences were detected. The agreement between the two methods was revealed by the Bland–Altman analysis. It was determined that the morphometric measurements performed were within the limits of agreement according to the Bland–Altman analysis. It was observed that the two measurement methods within the limits of agreement could be used as alternatives to each other. Conclusion: In conclusion, it is thought that the morphometric measurement results obtained from Akkaraman and Merino metacarpus will contribute to research examining the differences between breeds in sheep, as well as zooarchaeological and taxonomy studies.