Aim: The aim of this study is to evaluate the effects of face mask (FM) therapy combined with rapid maxillary expansion (RME) on airway dimensions in individuals with bilateral cleft lip and palate (BCLP). Methods: Individuals with BCLP who underwent RME and FM treatment (n=16, mean age: 11.4 ± 1.5 years; 9 females, 7 males) were included in the study. In this study, the archival records of the patients, including routine lateral cephalograms taken at the beginning and end of the treatment, were evaluated. Airway assessment was performed using Quick Ceph software. The results of the Shapiro-Wilk and Kolmogorov-Smirnov tests suggested that the data did not conform to a normal distribution. The significance level for the statistical analysis of the data was set at p ≤ 0.05, and the Wilcoxon Signed Rank Test was used. Results: After RME and FM therapy, an increase in SNA, ANB, and convexity angles, and a decrease in SNB were observed. In nasopharyngeal parameters, an increase was found in AD1-PNS, AD2-PNS, PNS-Ba, PNS-Ho, and PPS. Except for the increase in PNS-Ep and upper airway length, no statistically significant changes were observed in other oropharyngeal and hypopharyngeal parameters. Conclusion: In individuals with BCLP, RME and FM therapy may lead to an increase in nasopharyngeal airway dimensions.