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SCI-Expanded JCR Q1 Özgün Makale Scopus
A comparative analysis of techniques for measuring tumor contact length in predicting extraprostatic extension
European Journal of Radiology 2024
Scopus Eşleşmesi Bulundu
181
Cilt
Scopus Yazarları: Mehmet Arda İnan, Berrak Barutcu Asfuroğlu, Halil Özer, Umut Asfuroğlu, Murat Uçar
Özet
Purpose: This study aims to evaluate the diagnostic performance of curvilinear and linear measurement methods in different magnetic resonance imaging (MRI) sequences for detecting extraprostatic extension (EPE) in prostate cancer, and to evaluate the added value of apparent diffusion coefficient (ADC) in detecting EPE. Methods: A retrospective analysis was conducted on 84 patients who underwent multiparametric MRI (mp-MRI) prior to radical prostatectomy between January 2019 and February 2022. Tumor contact length (TCL) was assessed curvilinearly and linearly on T2-weighted imaging (T2WI), ADC maps, and dynamic contrast-enhanced (DCE) MRI by two radiologists. MRI-based EPE positivity was defined as a curvilinear or linear contact length of >15 mm. Statistical comparisons were conducted using chi-squared and independent samples t-tests, with interreader agreement evaluated using weighted κ statistics. Univariate and multivariate logistic regression identified independent predictors of EPE, and two prediction models were constructed. Diagnostic performance was assessed using receiver operator characteristic (ROC) curve analysis. Results: A total of 32 (38%) and 52 (62%) patients with EPE and non-EPE, respectively, were included in this study. Patients with EPE demonstrated significantly larger tumor sizes, lower ADC values, and lower ADC ratios than those without EPE (p < 0.001). The curvilinear and linear TCL measurements for each sequence exhibited statistically significant correlations with EPE for both readers, with strong interreader agreement. Curvilinear TCL (c-TCL) and linear TCL (l-TCL) on DCE-MRI showed higher area under the curve (AUC) values than the other measurements for EPE prediction (reader 1: 0.815 and 0.803, reader 2: 0.746 and 0.713, respectively). However, there was no statistically significant difference between c-TCL and l-TCL. Multivariable models with mean ADC value improved predictive performance. Model 2 (ADC, ISUP, and c-TCL on DCE images) surpassed model 1 (ADC and c-TCL on DCE images) with an AUC of 0.919 and 0.874, respectively. Conclusion: DCE-MRI demonstrated superior performance in predicting EPE compared to other sequences. Linear and curvilinear measurements had comparable diagnostic performance. Being more practical and easier, radiologists may use l-TCL measurement in daily practice. The mean ADC value provided additional diagnostic value.
Anahtar Kelimeler (Scopus)
Tumor contact length Multiparametric prostate MRI Prostate cancer Extraprostatic extension

Anahtar Kelimeler

Tumor contact length Multiparametric prostate MRI Prostate cancer Extraprostatic extension

Makale Bilgileri

Dergi European Journal of Radiology
ISSN 0720-048X
Yıl 2024 / 9. ay
Makale Türü Özgün Makale
Hakemlik Hakemli
Endeks SCI-Expanded
JCR Quartile Q1
TEŞV Puanı 36,00
Yayın Dili Türkçe
Kapsam Uluslararası
Toplam Yazar 5 kişi
Erişim Türü Basılı+Elektronik
Erişim Linki Makaleye Git
Alan Sağlık Bilimleri Temel Alanı Radyoloji

YÖKSİS Yazar Kaydı

Yazar Adı ASFUROĞLU UMUT,BARUTCU BERRAK,ÖZER HALİL,İNAN MEHMET ARDA,UÇAR MURAT
YÖKSİS ID 8044245

Metrikler

JCR Quartile Q1
TEŞV Puanı 36,00
Yazar Sayısı 5