This study aims to examine the relationship between parent resilience, couple burnout, and misogyny of fathers with disabled children, while also investigating the mediating effect of parent resilience on the relationship between misogyny and couple burnout. This study included a sample of 120 fathers whose children were attending a special education and rehabilitation center. Couple Burnout Scale Short Form, Misogyny Scale, Family Resilience Scale, and Personal Information Form were used as instruments in the study. The findings revealed a significant relationship between couple burnout and levels of misogyny, as well as a negative relationship between couple burnout and perception of parent resilience. Additionally, a negative relationship was observed between the level of misogyny and parent resilience. Importantly, parent resilience was found to mediate the relationship between level of misogyny and couple burnout, explaining 24.5% of the total variance. Based on these findings, it is recommended to prioritize psychological interventions that strengthen resilience of fathers with disabled children.