Achillea alimeana Semiz & Uysal sp. nov. of sect. Santolinoidea DC. (Asteraceae), was described, diagnosed and illustrated as a new species. It was collected from Akdağ Mountains in Denizli Province. In this paper, the diagnostic characters of A. alimeana and its similar species were discussed in the morphological, palynological and molecular findings. As regards the new species, some notes on the ecology, conservation status, and distribution were submitted. A diagnostic key was given for related taxa.