Inorganic selenium supplementation in poultry diet has been controversial. It has been linked that the excess and deficiency of this mineral can lead to health problems in these animals. However, this fact is not so evident in quails. In this research 120 female quails (220.6 ± 8.2 g) at 10 weeks of age were allocated to five treatment groups with six replicates of four quails in each. Experimental diets were formed by adding 0, 0.25, 0.50, 0.75 or 1.00 mg/kg of inorganic selenium (sodium-selenite) to the diet containing 0.12 mg/kg of selenium. We observed that performance parameters, mortality, egg external, and internal quality of quails were not affected by the supplementation of inorganic selenium to the diet Serum glucose (P = 0.0020) and creatinine (P = 0.0333) levels were affected by inorganic selenium supplementation, but no differences were found for other parameters among those treatments. The addition of 0.50 mg/kg of inorganic selenium to the diet increased serum glucose levels of laying quails compared with the control group. While serum creatinine level was maximized with the addition of 0.25 mg/kg inorganic selenium to the diet, and it was minimized with the addition of 0.50 mg/kg inorganic selenium. Supplementation with inorganic selenium (0 to 1.00 mg/kg) in laying quail diets did not have any adverse effect on performance, mortality, and egg quality during the study. No abnormalities were found in the serum parameters that would lead to the suspicion of metabolic disease in the quails.