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ESCI Özgün Makale Scopus
Dosimetric Comparison of Three-Dimensional ConformalRadiotherapy, Dynamic Intensity Modulated Radiation Therapy, and Hybrid Planning for Treatment of Locally Advanced Lung Cancer
Middle East Journal of Cancer 2022 Cilt 13 Sayı 3
Scopus Eşleşmesi Bulundu
1
Atıf
13
Cilt
523-530
Sayfa
Scopus Yazarları: Hamit Basaran, Gokcen Inan, Osman Vefa Gul, Mursel Duzova
Özet
Background: The present dosimetric study aimed to evaluate the dosimetric benefits of using three-dimensional conformal radiotherapy (3D-CRT), dynamic intensity-modulated radiation therapy (D-IMRT), and Hybrid CRT/IMRT plans. Method: In this dosimetric research, 10 patients with locally advanced lung cancer (Stage-IIIB) were selected. The patients with centrally located tumors were particularly chosen to underline the complexity of the treatment plans. We performed 3D-CRT, D-IMRT, and Hybrid CRT/IMRT treatment plans using Varian with the Eclipse treatment planning system. The treatment plans were compared with respect to the doses received by the organs at risk, including total lungs, contralateral lung, ipsilateral lung, heart, spinal cord, esophagus, the dose homogeneity index, and conformity indexes. Paired samples t-test was performed for statistical analyses. Results: Hybrid method significantly advanced the target conformity index when compared with 3D-CRT and D-IMRT methods (P = 0.000). The total lung volume receiving 5 to 10 Gy was significantly lower in the 3D-CRT plans compared with that in D-IMRT and Hybrid plans (P = 0.025 and P = 0.003). V20 of the total lung was significantly lower in Hybrid plans (P =0.036). The average mean doses to heart in all the plans were similar with no significant differences. There was a statistically significant difference concerning the maximum doses for spinal cord, when D-IMRT plans were compared with 3D-CRT and Hybrid (P = 0.000). Conclusion: Hybrid technique could be highly conducive to the treatment, while 3D-CRT and D-IMRT techniques are not adequate alone for maintaining the spinal cord, heart, and esophagus in the treatment of LALC patients.
Anahtar Kelimeler (Scopus)
Intensity-modulated radiotherapy Lung neoplasms Three-dimensional conformal radiotherapy

Anahtar Kelimeler

Intensity-modulated radiotherapy Lung neoplasms Three-dimensional conformal radiotherapy

Makale Bilgileri

Dergi Middle East Journal of Cancer
ISSN 2008-6709
Yıl 2022 / 7. ay
Cilt / Sayı 13 / 3
Sayfalar 523 – 530
Makale Türü Özgün Makale
Hakemlik Hakemli
Endeks ESCI
Yayın Dili İngilizce
Kapsam Uluslararası
Toplam Yazar 4 kişi
Erişim Türü Elektronik
Erişim Linki Makaleye Git
Alan Sağlık Bilimleri Temel Alanı Sağlık Fiziği

YÖKSİS Yazar Kaydı

Yazar Adı BAŞARAN HAMİT,İNAN GÖKÇEN,GÜL OSMAN VEFA,DÜZOVA MÜRSEL
YÖKSİS ID 6353108