SCI-Expanded
JCR Q1
Özgün Makale
Scopus
The dosimetric comparison and evaluation of helical tomotherapy, volumetric-modulated arc radiotherapy (VMAT), step-and-shoot and sliding window radiotherapy techniques in nasopharyngeal carcinoma
Radiation Physics and Chemistry
2022
Cilt 193
Scopus Eşleşmesi Bulundu
3
Atıf
193
Cilt
Scopus Yazarları: Hikmettin Demir, Serhat Aras, Nihal Buyukcizmeci, Berrin Benli Yavuz
Özet
The aim of this study was to dosimetrically compare treatment plans prepared with volumetric-modulated arc radiotherapy (VMAT), tomotherapy, step-and-shoot and sliding radiotherapy techniques in nasopharyngeal cancer (NPC) and to evaluate the superiority of different techniques in routine clinical practice. Treatment plans obtained by VMAT, tomotherapy, step and shoot and sliding window techniques were evaluated for twenty NPC patients. Different treatment plans were prepared by using the simultaneous integrated boost (SIB) technique in 35 fractions of 70Gy to primary planning target volume and 56Gy to elective lymph nodes. While NPC treatment plans were obtained in four different radiotherapy techniques, 95% of the target volumes were provided with defined dose coverage and critical organs received the lowest possible dose. In addition to the doses received by target tissues and critical organs, dose delivered time, monitor unit (MU), dose homogeneity (HI) and conformity (CI) index were compared for different radiotherapy techniques. The D95 dose coverage and lowest maximum dose values (Dmax) are better achieved in the tomotherapy technique for primary tumor and elective lymph node target volumes. However, the lowest dose coverage is obtained in the step-and-shoot technique (p < 0.05). Although the highest MU value was calculated in tomotherapy, the lowest delivered time was also achieved in the VMAT technique. It was observed that different radiotherapy techniques had advantages and disadvantages compared to each other at certain dose-volume constraints (Dmax, Dmin, Dmean, D1, and V30) for organs at risk. Although the tomotherapy technique was better in target volume dose coverage, it was observed that other techniques had superiority over each other in terms of protection of organs at risk and dosimetric parameters for NPC patients.
Anahtar Kelimeler (Scopus)
Nasopharyngeal cancer
Sliding window
Step-and-shoot
Tomotherapy
VMAT
Anahtar Kelimeler
Nasopharyngeal cancer
Sliding window
Step-and-shoot
Tomotherapy
VMAT
Makale Bilgileri
Dergi
Radiation Physics and Chemistry
ISSN
0969-806X
Yıl
2022
/ 1. ay
Cilt / Sayı
193
Makale Türü
Özgün Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
JCR Quartile
Q1
TEŞV Puanı
81,00
Yayın Dili
İngilizce
Kapsam
Uluslararası
Toplam Yazar
4 kişi
Erişim Türü
Elektronik
Erişim Linki
Makaleye Git
Alan
Fen Bilimleri ve Matematik Temel Alanı
Fizik
Medikal Fizik
Radyofizik
Nükleer Fizik
YÖKSİS Yazar Kaydı
Yazar Adı
DEMİR HİKMETTİN, ARAS SERHAT, BÜYÜKÇİZMECİ NİHAL, BENLİ YAVUZ BERRİN
YÖKSİS ID
6350336
Hızlı Erişim
Metrikler
Scopus Atıf
3
JCR Quartile
Q1
TEŞV Puanı
81,00
Yazar Sayısı
4