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SCI-Expanded JCR Q2 Özgün Makale Scopus
Evaluation of ovarian reserve in women with overt or subclinical hypothyroidism
Archives of Medical Science 2018 Cilt 14
Scopus Eşleşmesi Bulundu
17
Atıf
14
Cilt
521-526
Sayfa
🔓
Açık Erişim
Scopus Yazarları: Umit Gorkem, Yasin Simsek, Ramazan Kocabaş, Serdar Guler, Ferit Kerim Kucukler
Özet
Introduction: Thyroid dysfunction is among the most common autoimmune disorders in women of reproductive age. Previous studies have shown the association between autoimmune thyroid disease (AITD) and infertility. Anti-Müllerian hormone (AMH) is secreted by granulosa cells and is a useful marker for assessment of ovarian reserve. In the present study, we sought to evaluate the ovarian reserves of women with autoimmune thyroid disorder by measurement of AMH values. Material and methods: This prospective study included women with newly diagnosed AITD aged between 20 and 40 years. Patients were divided into three groups: Subclinical hypothyroidism (SCH, n = 21), overt hypothyroidism (OH, n = 21) and controls (CG, n = 32). Study parameters included serum free T4, free T3, thyroid-stimulating hormone, anti-thyroglobulin, anti-thyroid peroxidase antibodies, follicle-stimulating hormone, luteinizing hormone, estradiol and AMH concentrations measured in the early follicular phase. Antral follicle count (AFC) was assessed with ultrasound. Body mass index (BMI) and waist circumference of the patients were noted. Results: No significant difference was found among SCH, OH and CG in regard to ovarian reserves measured by AMH values (p = 0.19) and AFC (p = 0.80). A significant negative correlation was found between AMH and BMI (r = -0.382, p = 0.001). Anti-Müllerian hormone and waist circumference (r = -0.330, p = 0.004) were also negatively correlated. Conclusions: Although AMH values were not significantly different among groups, AMH values were lower in OH and SCH patients, indicating a possible need for close monitoring of these patients.
Anahtar Kelimeler (Scopus)
Anti-Müllerian hormone Autoimmune thyroid disease Fertile women

Anahtar Kelimeler

Anti-Müllerian hormone Autoimmune thyroid disease Fertile women

Makale Bilgileri

Dergi Archives of Medical Science
ISSN 1734-1922
Yıl 2018 / 1. ay
Cilt / Sayı 14
Makale Türü Özgün Makale
Hakemlik Hakemli
Endeks SCI-Expanded
JCR Quartile Q2
TEŞV Puanı 144,00
Yayın Dili Türkçe
Kapsam Uluslararası
Toplam Yazar 5 kişi
Erişim Türü Elektronik
Erişim Linki Makaleye Git
Alan Sağlık Bilimleri Temel Alanı TIP

YÖKSİS Yazar Kaydı

Yazar Adı KÜÇÜKLER FERİT KERİM, GÖRKEM ÜMİT, ŞİMŞEK YASİN, KOCABAŞ RAMAZAN, GÜLER SERDAR
YÖKSİS ID 5289008

Metrikler

Scopus Atıf 17
JCR Quartile Q2
TEŞV Puanı 144,00
Yazar Sayısı 5