Relativistic collisions of ions, hadrons and leptons with nuclei can produce various hypernuclei by the capture of hyperons in nuclear residues. In many cases the disintegration of such hypernuclear systems can be described with statistical approaches suggesting that the fragment production is related to the binding energies of hypernuclei. We demonstrate how the hyperon binding energies can be effectively evaluated from the yields of different hyper-isotopes using the double ratio method. Its universality and the possibility to involve many different isotopes are the advantages of this method. The same procedure can also be applied for multi-strange nuclei, for which binding energies were very difficult to measure in previous hypernuclear experiments. Modifications caused by secondary de-excitation processes in hot hypernuclei are considered additionally.